2022 Fiscal Year Final Research Report
An attempt to predict prognosis of psychotic disorders by a combination of biomarkers
| Project/Area Number |
18K07550
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 52030:Psychiatry-related
|
|---|
| Research Institution | University of Toyama |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
樋口 悠子 富山大学, 学術研究部医学系, 講師 (60401840)
笹林 大樹 富山大学, 学術研究部医学系, 助教 (80801414)
|
|---|
| Project Period (FY) |
2018-04-01 – 2023-03-31
|
| Keywords | 統合失調症 / 精神病発症危険状態 / 磁気共鳴画像 / 嗅覚機能 / 事象関連電位 |
|---|
| Outline of Final Research Achievements |
The later onset of psychotic disorders in individuals at clinical high-risk state and the later clinical course of first-episode schizophrenia patients could be predicted with a certain degree of accuracy by biomarkers obtained by magnetic resonance imaging and event-related potentials, and a combination of findings was particularly useful in improving the prediction accuracy.
|
| Free Research Field |
精神医学
|
| Academic Significance and Societal Importance of the Research Achievements |
精神疾患に対する早期介入の臨床的有用性が広く認識されつつあるが、精神科早期介入における客観的検査所見の役割はわかっていない。今回の研究により、脳画像検査や脳波検査が精神疾患の経過予測に有用である可能性が示された。
|
