2021 Fiscal Year Annual Research Report
Novel nanomaterials and hybrid soft contact lens for removing fluorouracil from the tear of cancer patients
| Project/Area Number |
18K09469
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
Ding Wuxiao 国立研究開発法人産業技術総合研究所, 材料・化学領域, 主任研究員 (90598757)
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| Project Period (FY) |
2018-04-01 – 2022-03-31
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| Keywords | Hybrid hydrogel / Nanotube / Contact lens |
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| Outline of Annual Research Achievements |
In the 2021 fiscal year, a hybrid hydrogel was constructed from the PEG polymer and crosslinkable nanotube, the inclusion of nanotube significantly increased the mechanical strength and controlled release property of PEG hydrogel.The nanotube-hybrid hydrogel may have potential application in contact lens. This finding suggested that PEGylation the melamine-nanoparticles could be effective in inproving the dispersibility and transparency issues in the melamine-nanoparticles hybrided contact lens. The related work was published in Polymer Journal (2022) 54:67-78;
Further, biodegradable supramolecular nanotube tailored for bio-responsive delivery nanocarrier was also constructed. The related work was published in Chem. Lett. 2021, 50, 1743-1746.
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