2023 Fiscal Year Final Research Report

Elucidation of mechanism of pain-relief by transplanting endothelial progenitor cells to treat critical limb ischemia

Research Project

Project/Area Number	18K09493
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Review Section	Basic Section 56070:Plastic and reconstructive surgery-related
Research Institution	Juntendo University
Principal Investigator	Hagiwara Hiroko 順天堂大学, 大学院医学研究科, 非常勤講師 (30589429)
Co-Investigator(Kenkyū-buntansha)	田中里佳順天堂大学, 医学部, 教授 (70509827) 櫻田司第一薬科大学, 薬学部, 名誉教授 (80124907)
Project Period (FY)	2018-04-01 – 2023-03-31
Keywords	再生医療
Outline of Final Research Achievements	Our study elucidated a part of mechanism of pain-relief by transplanting endothelial progenitor cells to critical limb ischemia patients.
Free Research Field	再生医療
Academic Significance and Societal Importance of the Research Achievements	世界的な糖尿病罹患率の増加に伴い、重症下肢虚血患者数も増加しており、動物モデルの確立及び、患者QOLを著しく低下させる間性疼痛の軽減メカニズムの解明は、学術的にも社会的にも意義があるものである。