Consideration of effective skin care based on the relationship between skin barrier function and perceptional threshold

2021 Fiscal Year Final Research Report

• Project/Area Number: 18K10233
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58050:Fundamental of nursing-related
• Research Institution: Ehime University
• Principal Investigator: Saeki Yuka 愛媛大学, 医学系研究科, 教授 (70211927)
• Project Period (FY): 2018-04-01 – 2022-03-31
• Keywords: 皮膚バリア機能 / 電流知覚閾値 / 疼痛閾値 / 経表皮水分蒸散量

Outline of Final Research Achievements

The purpose of this study was to clarify the relationship between skin barrier function and skin perceptual threshold. The skin barrier function was evaluated by measuring the transepidermal water loss (TEWL), and skin perceptual threshold by measuring the current perceptual threshold (CPT) and the pain threshold (PT). TEWL was deliberately altered by using 2% sodium lauryl sulfate solution on the palm side of the forearm. As a result, CPT and PT decrease as TEWL increased. In addition, TEWL and CPT or PT showed a significantly negative correlation. Therefore, it was concluded that hypersensitivity must occur when the skin barrier function is decreased.

Free Research Field

看護生理学

Academic Significance and Societal Importance of the Research Achievements

アトピー性皮膚炎などでは皮膚バリア機能が低下しており、バリア機能の低下が長引くと掻痒など知覚にも影響を及ぼす。医療・介護現場では、乾燥した環境や医療用粘着テープの使用など、皮膚バリア機能が低下しやすい状況にある。さらに看護実践でよく行う清潔ケアでは、対象者の肌を直接刺激することが多い。しかしながら、対象者の皮膚感覚を考慮しながらケアを行うことはほとんどない。しかし、今後は皮膚バリア機能の状況を考慮しながらスキンケアを行う必要性を示した。