Development and effectiveness of a multi-patient physical activity monitoring system

2020 Fiscal Year Annual Research Report

• Project/Area Number: 18K10757
• Research Institution: Kitasato University
• Principal Investigator: 神谷 健太郎 北里大学, 医療衛生学部, 教授 (10448970)
• Project Period (FY): 2018-04-01 – 2021-03-31
• Keywords: 心不全 / 身体活動 / モニタリング

Outline of Annual Research Achievements

心不全患者の運動機能が急激に悪化する契機となる代表的なものに再発に伴う入院があり、入院中の身体活動量の低下がその大きな要因であることが指摘されている。本研究代表者は、入院中の身体活動量モニタリングが、身体機能低下の予防に有用なのではないかと考え、本研究を遂行した。
2018年度は、ウェアラブルデバイス数種類を用いて、高齢心不全患者の身体活動量評価において信頼性、妥当性の高い機器を選出すること、またその結果を一覧で表示出来るダッシュボードの開発を行える企業を選出することを主な活動とした。複数の企業と交渉した後、本研究で用いる多人数の活動量管理システムを予算内で開発可能である国内企業と、開発計画の策定を開始した。
2019年度には、上記の企業と共同で入院中の患者の身体活動量をNFC搭載のPC端末で収集し、それを一覧表示させる機能を有するシステムの開発をおこなった。本システムでは、患者に対応した活動量計をNFC端末に接触させることでパソコンにデータを収集し、新たに開発したダッシュボードを用いて活動量の低い患者をスクリーニングすることができる。このシステムはインターネットに接続しないスタンドアローンのPCで導入可能なシステムである。
2020年度には、本システムを用い、単施設のパイロット研究を実施した。本システムを使用した心不全患者からは、自らの身体活動量の推移が把握でき、モチベーションの向上につながるとの回答が得られた。また、医療従事者からも、集中的に介入すべき対象者が容易に特定出来るとの利点が確認出来た。
次年度以降は、本研究で開発した機器を用いて、当施設で行ったパイロット研究の成果をもとに、多施設前向き介入研究を実施予定である。

Research Products

• [Journal Article] The GLIM criteria for defining malnutrition can predict physical function and prognosis in patients with cardiovascular disease (2021)
  • Author(s): Kootaka Y, Kamiya K, Hamazaki N, Nozaki K, Ichikawa T, Nakamura T, Yamashita M, Maekawa E, Reed JL, Yamaoka-Tojo M, Matsunaga A, Ako J.
  • Journal Title: Clin Nutr Volume: 40 Pages: 146-152
  • DOI: 10.1016/j.clnu.2020.04.038
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Quadriceps Strength and Mortality in Older Patients With Heart Failure (2021)
  • Author(s): Nakamura T, Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Ichikawa T, Yamashita M, Maekawa E, Reed JL, Noda C, Meguro K, Yamaoka-Tojo M, Matsunaga A, Ako J.
  • Journal Title: Can J Cardiol Volume: 37 Pages: 476-483
  • DOI: 10.1016/j.cjca.2020.06.019
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Perceived difficulty in activities of daily living and survival in patients receiving maintenance hemodialysis (2021)
  • Author(s): Watanabe T, Kutsuna T, Suzuki Y, Harada M, Shimoda T, Yamamoto S, Isobe Y, Imamura K, Matsunaga Y, Matsuzawa R, Kamiya K, Takeuchi Y, Yoshida A, Matsunaga A.
  • Journal Title: Int Urol Nephrol Volume: 53 Pages: 177-184
  • DOI: 10.1007/s11255-020-02600-0
  • Peer Reviewed
• [Journal Article] Prevalence and prognostic value of the coexistence of anaemia and frailty in older patients with heart failure (2021)
  • Author(s): Tanaka S, Kamiya K, Saito H, Saito K, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Hamazaki N, Nozaki K, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Wakaume K, Oka K, Momomura SI, Kagiyama N, Matsue Y.
  • Journal Title: ESC Heart Fail Volume: 8 Pages: 625-633
  • DOI: 10.1002/ehf2.13140
  • Peer Reviewed / Open Access
• [Journal Article] Prevalence and prognostic implications of malnutrition as defined by GLIM criteria in elderly patients with heart failure (2021)
  • Author(s): Hirose S, Matsue Y, Kamiya K, Kagiyama N, Hiki M, Dotare T, Sunayama T, Konishi M, Saito H, Saito K, Ogasahara Y, Maekawa E, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Momomura SI, Minamino T.
  • Journal Title: Clin Nutr Volume: － Pages: －
  • DOI: 10.1016/j.clnu.2021.01.014
  • Peer Reviewed
• [Journal Article] Prognostic value of cardio-hepatic-skeletal muscle syndrome in patients with heart failure (2021)
  • Author(s): Noda T, Kamiya K, Hamazaki N, Nozaki K, Ichikawa T, Nakamura T, Yamashita M, Uchida S, Maekawa E, Reed JL, Yamaoka-Tojo M, Matsunaga A, Ako J.
  • Journal Title: Sci Rep Volume: 11 Pages: 3715
  • DOI: 10.1038/s41598-020-80641-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Post-intensive care syndrome as a predictor of mortality in patients with critical illness: A cohort study (2021)
  • Author(s): Yanagi N, Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Ichikawa T, Valley TS, Nakamura T, Yamashita M, Maekawa E, Koike T, Yamaoka-Tojo M, Arai M, Matsunaga A, Ako J.
  • Journal Title: PLoS One Volume: 16 Pages: e0244564
  • DOI: 10.1371/journal.pone.0244564
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Validity and Utility of the Questionnaire-based FRAIL Scale in Older Patients with Heart Failure: Findings from the FRAGILE-HF (2021)
  • Author(s): Nozaki K, Kamiya K, Hamazaki N, Saito H, Saito K, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Makino A, Oka K, Momomura SI, Kagiyama N, Matsue Y.
  • Journal Title: J Am Med Dir Assoc Volume: － Pages: －
  • DOI: 10.1016/j.jamda.2021.02.025
  • Peer Reviewed
• [Journal Article] Low skeletal muscle density combined with muscle dysfunction predicts adverse events after adult cardiovascular surgery (2021)
  • Author(s): Yamashita M, Kamiya K, Matsunaga A, Kitamura T, Hamazaki N, Nozaki K, Ichikawa T, Maekawa E, Meguro K, Yamaoka-Tojo M, Ako J, Miyaji K.
  • Journal Title: Nutr Metab Cardiovasc Dis Volume: － Pages: －
  • DOI: 10.1016/j.numecd.2021.02.012
  • Peer Reviewed
• [Journal Article] Rising time from bed in acute phase after hospitalization predicts frailty at hospital discharge in patients with acute heart failure (2020)
  • Author(s): Nozaki K, Hamazaki N, Kamiya K, Ichikawa T, Nakamura T, Yamashita M, Maekawa E, Matsunaga A, Yamaoka-Tojo M, Ako J.
  • Journal Title: J Cardiol Volume: 75 Pages: 587-593
  • DOI: 10.1016/j.jjcc.2019.12.007
  • Peer Reviewed
• [Journal Article] Association between sarcopenia and atherosclerosis in elderly patients with ischemic heart disease (2020)
  • Author(s): Uchida S, Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Ichikawa T, Suzuki Y, Nakamura T, Yamashita M, Kariya H, Maekawa E, Yamaoka-Tojo M, Matsunaga A, Ako J.
  • Journal Title: Heart Vessels Volume: 35 Pages: 769-775
  • DOI: 10.1007/s00380-020-01554-8
  • Peer Reviewed
• [Journal Article] Usefulness of the Simplified Frailty Scale in Predicting Risk of Readmission or Mortality in Elderly Patients Hospitalized with Cardiovascular Disease (2020)
  • Author(s): Aida K, Kamiya K, Hamazaki N, Matsuzawa R, Nozaki K, Ichikawa T, Nakamura T, Yamashita M, Maekawa E, Yamaoka-Tojo M, Matsunaga A, Ako J.
  • Journal Title: Int Heart J Volume: 61 Pages: 571-578
  • DOI: 10.1536/ihj.19-557
  • Peer Reviewed / Open Access
• [Journal Article] Prevalence and prognostic impact of the coexistence of multiple frailty domains in elderly patients with heart failure: the FRAGILE-HF cohort study (2020)
  • Author(s): Matsue Y, Kamiya K, Saito H, Saito K, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Yonezawa R, Oka K, Momomura SI, Kagiyama N.
  • Journal Title: Eur J Heart Fail Volume: 22 Pages: 2112-2119
  • DOI: 10.1002/ejhf.1926
  • Peer Reviewed
• [Journal Article] Cognitive impairment measured by Mini-Cog provides additive prognostic information in elderly patients with heart failure (2020)
  • Author(s): Saito H, Yamashita M, Endo Y, Mizukami A, Yoshioka K, Hashimoto T, Koseki S, Shimode Y, Kitai T, Maekawa E, Kasai T, Kamiya K, Matsue Y.
  • Journal Title: J Cardiol Volume: 76 Pages: 350-356
  • DOI: 10.1016/j.jjcc.2020.06.016
  • Peer Reviewed
• [Journal Article] Japanese Heart Failure Society 2018 Scientific Statement on Nutritional Assessment and Management in Heart Failure Patients (2020)
  • Author(s): Yamamoto K, Tsuchihashi-Makaya M, Kinugasa Y, Iida Y, Kamiya K, Kihara Y, Kono Y, Sato Y, Suzuki N, Takeuchi H, Higo T, Miyazawa Y, Miyajima I, Yamashina A, Yoshita K, Washida K, Kuzuya M, Takahashi T, Nakaya Y, Hasebe N, Tsutsui H; Japanese Heart Failure Society, Expert Consensus Writing Committee.
  • Journal Title: Circ J Volume: 84 Pages: 1408-1444
  • DOI: 10.1253/circj.CJ-20-0322
  • Peer Reviewed / Open Access
• [Journal Article] Prognostic value of pupil area for all-cause mortality in patients with heart failure (2020)
  • Author(s): Nozaki K, Hamazaki N, Yamamoto S, Kamiya K, Tanaka S, Ichikawa T, Nakamura T, Yamashita M, Maekawa E, Matsunaga A, Yamaoka-Tojo M, Ako J.
  • Journal Title: ESC Heart Fail Volume: 7 Pages: 3067-3074
  • DOI: 10.1002/ehf2.12933
  • Peer Reviewed / Open Access
• [Journal Article] Modified Creatinine Index and Clinical Outcomes of Hemodialysis Patients: An Indicator of Sarcopenia? (2020)
  • Author(s): Yamamoto S, Matsuzawa R, Hoshi K, Suzuki Y, Harada M, Watanabe T, Isobe Y, Imamura K, Osada S, Yoshida A, Kamiya K, Matsunaga A.
  • Journal Title: J Ren Nutr Volume: － Pages: －
  • DOI: 10.1053/j.jrn.2020.08.006
  • Peer Reviewed
• [Journal Article] Multidisciplinary Cardiac Rehabilitation and Long-Term Prognosis in Patients With Heart Failure (2020)
  • Author(s): Kamiya K, Sato Y, Takahashi T, Tsuchihashi-Makaya M, Kotooka N, Ikegame T, Takura T, Yamamoto T, Nagayama M, Goto Y, Makita S, Isobe M.
  • Journal Title: Circ Heart Fail Volume: 13 Pages: e006798
  • DOI: 10.1161/CIRCHEARTFAILURE.119.006798
  • Peer Reviewed / Open Access
• [Journal Article] Impact of Physical Activity on Dialysis and Nondialysis Days and Clinical Outcomes Among Patients on Hemodialysis (2020)
  • Author(s): Yamamoto S, Matsuzawa R, Hoshi K, Harada M, Watanabe T, Suzuki Y, Isobe Y, Imamura K, Osada S, Yoshida A, Kamiya K, Matsunaga A.
  • Journal Title: J Ren Nutr Volume: － Pages: －
  • DOI: 10.1053/j.jrn.2020.07.007
  • Peer Reviewed
• [Journal Article] Effect of atrial fibrillation on response to exercise-based cardiac rehabilitation in older individuals with heart failure (2020)
  • Author(s): Hamazaki N, Kamiya K, Fukaya H, Nozaki K, Ichikawa T, Matsuzawa R, Yamashita M, Uchida S, Maekawa E, Meguro K, Yamaoka-Tojo M, Matsunaga A, Ako J.
  • Journal Title: Ann Phys Rehabil Med Volume: － Pages: －
  • DOI: 10.1016/j.rehab.2020.101466
  • Peer Reviewed
• [Journal Article] Impact of sarcopenia on prognosis in patients with heart failure with reduced and preserved ejection fraction (2020)
  • Author(s): Konishi M, Kagiyama N, Kamiya K, Saito H, Saito K, Ogasahara Y, Maekawa E, Misumi T, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Makino A, Oka K, Momomura SI, Matsue Y.
  • Journal Title: Eur J Prev Cardiol Volume: － Pages: －
  • DOI: 10.1093/eurjpc/zwaa117
  • Peer Reviewed
• [Presentation] フレイル心不全患者に対する心臓リハビリテーション (2020)
  • Author(s): 神谷健太郎
  • Organizer: 第24回日本心不全学会学術集会
• [Presentation] 心不全急性期から始める心臓リハビリテーション (2020)
  • Author(s): 神谷健太郎
  • Organizer: 第75回日本循環器学会学術集会
• [Presentation] 各疾患別リハビリテーションのエビデンスの現状と今後の課題 ―学術活動の重要性を再考する― (2020)
  • Author(s): 神谷健太郎
  • Organizer: 第 30 回日本呼吸ケア・リハビリテーション学会学術集会
  • Invited
• [Patent(Industrial Property Rights)] 活動量モニタリングシステムおよび活動量ニタリング方法 (2020)
  • Inventor(s): 神谷健太郎
  • Industrial Property Rights Holder: 学校法人北里研究所
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 特願２０２０－２６４０８