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2018 Fiscal Year Research-status Report

The effects of connectin (titin) on muscle and joint function before and after eccentric contractions

Research Project

Project/Area Number 18K10832
Research InstitutionHosei University

Principal Investigator

越智 英輔  法政大学, 生命科学部, 准教授 (90468778)

Co-Investigator(Kenkyū-buntansha) 中里 浩一  日本体育大学, 保健医療学部, 教授 (00307993)
菊池 直樹  日本体育大学, 体育学部, 助教 (10739478)
Project Period (FY) 2018-04-01 – 2022-03-31
Keywords遺伝子多型 / コネクチン / タイチン / 関節柔軟性
Outline of Annual Research Achievements

本年度はコネクチン(TITIN)遺伝子多型に着目し、予備的に関節柔軟性を多型別に解析した。具体的には、身体的特徴、関節柔軟性、無酸素性パワー、ジャンプパフォーマンス、酸化ストレスマーカーを多型別に分析した。対象は大学体育会所属学生とした。その結果、TITIN遺伝子多型は、CC13名、CT13名、TT0名であった。TITIN多型別およびアレル別に解析したところ、肩関節・肘関節の柔軟性と多型との関連は認められなかった。さらに、身体的特徴、無酸素パワー、ジャンプパフォーマンス、酸化ストレスマーカー、競技レベルなどについても関連性が認められなかった。
上記実験に加えて、分担研究者とヒトを対象とした運動負荷実験、遺伝子改変ラットの作成に関する打ち合わせを実施した。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

予備的なヒト実験を完了することができたため

Strategy for Future Research Activity

ヒトを対象とした運動負荷実験を実施し、さらに分担研究者と共に遺伝子改変ラットの作成を進める

Causes of Carryover

前倒し請求した金額と購入品とに差額が生じたため、次年度の出張経費に充てることとした。

  • Research Products

    (9 results)

All 2019 2018

All Journal Article (9 results) (of which Peer Reviewed: 9 results)

  • [Journal Article] Short‐term cycling restores endothelial dysfunction after resistance exercise2019

    • Author(s)
      Morishima Takuma、Iemitsu Motoyuki、Ochi Eisuke
    • Journal Title

      Scandinavian Journal of Medicine & Science in Sports

      Volume: 29 Pages: 1115~1120

    • DOI

      10.1111/sms.13434

    • Peer Reviewed
  • [Journal Article] Muscular recruitment is associated with muscular function and swelling following eccentric contractions of human elbow flexors2019

    • Author(s)
      Tsuchiya Yosuke、Ueda Hisashi、Ochi Eisuke
    • Journal Title

      The Journal of sports medicine and physical fitness

      Volume: - Pages: -

    • Peer Reviewed
  • [Journal Article] Eicosapentaenoic Acid-Rich Fish Oil Supplementation Inhibits the Decrease in Concentric Work Output and Muscle Swelling of the Elbow Flexors.2019

    • Author(s)
      Ochi Eisuke、Yanagimoto Kenichi、Morishima Takuma、Tsuchiya Yosuke.
    • Journal Title

      Journal of the American College of Nutrition

      Volume: 38 Pages: 125-131

    • Peer Reviewed
  • [Journal Article] Eicosapentaenoic Acid (EPA) and Docosahexaneoic Acid (DHA) in Muscle Damage and Function2018

    • Author(s)
      Ochi Eisuke、Tsuchiya Yosuke
    • Journal Title

      Nutrients

      Volume: 10 Pages: 552~552

    • DOI

      10.3390/nu10050552

    • Peer Reviewed
  • [Journal Article] Seasonal Variations of Bone Metabolism and Bone Mineral Density in Collegiate Alpine Skiers2018

    • Author(s)
      Sato Teruyuki、Sakuraba Keishoku、Tsuchiya Yosuke、Maruyama Shinya、Ochi Eisuke
    • Journal Title

      Journal of Strength and Conditioning Research

      Volume: 32 Pages: 1448~1454

    • DOI

      10.1519/JSC.0000000000001987

    • Peer Reviewed
  • [Journal Article] Higher Training Frequency Is Important for Gaining Muscular Strength Under Volume-Matched Training2018

    • Author(s)
      Ochi Eisuke、Maruo Masataka、Tsuchiya Yosuke、Ishii Naokata、Miura Koji、Sasaki Kazushige
    • Journal Title

      Frontiers in Physiology

      Volume: 9 Pages: 744

    • DOI

      10.3389/fphys.2018.00744

    • Peer Reviewed
  • [Journal Article] Contralateral repeated bout effect after eccentric exercise on muscular activation2018

    • Author(s)
      Tsuchiya Yosuke、Nakazato Koichi、Ochi Eisuke
    • Journal Title

      European Journal of Applied Physiology

      Volume: 118 Pages: 1997~2005

    • DOI

      doi: 10.1007/s00421-018-3933-9

    • Peer Reviewed
  • [Journal Article] High-intensity resistance exercise with low repetitions maintains endothelial function2018

    • Author(s)
      Morishima Takuma、Tsuchiya Yosuke、Iemitsu Motoyuki、Ochi Eisuke
    • Journal Title

      American Journal of Physiology-Heart and Circulatory Physiology

      Volume: 315 Pages: H681~H686

    • DOI

      10.1152/ajpheart.00281.2018

    • Peer Reviewed
  • [Journal Article] Two and Four Weeks of β-Hydroxy-β-Methylbutyrate (HMB) Supplementations Reduce Muscle Damage Following Eccentric Contractions2018

    • Author(s)
      Tsuchiya Yosuke、Hirayama Kinjiro、Ueda Hisashi、Ochi Eisuke.
    • Journal Title

      Journal of the American College of Nutrition

      Volume: 27 Pages: 1-7

    • Peer Reviewed

URL: 

Published: 2022-12-28  

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