Constructing a Learning Design for Schizophrenia with a Focus on Timing Impairment

2022 Fiscal Year Final Research Report

• Project/Area Number: 18K13363
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 10030:Clinical psychology-related
• Research Institution: National Center of Neurology and Psychiatry
• Principal Investigator: Ueda Natsuki 国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 行動医学研究部, リサーチフェロー (50807922)
• Project Period (FY): 2018-04-01 – 2023-03-31
• Keywords: 時間知覚 / 知覚推論 / 精神疾患

Outline of Final Research Achievements

The purpose of this study was to clarify changes in time perception in schizophrenia. First, we focused on dopaminergic changes related to psychological time in neurological disorders such as schizophrenia and Tourette's syndrome, and found the changes in time perception in these disorders. In addition to this, based on a hypothesis that patients with schizophrenia are associated with an abnormal weighting of prior in perceptual inference, we conducted behavioral experiments and found changes in the strategies of perceptual inference in patients with schizophrenia.

Free Research Field

認知神経科学

Academic Significance and Societal Importance of the Research Achievements

精神疾患における知覚の変化については古くから報告されているものの未だ不明な点が多く，治療標的は未だ不明な点が多い．本研究により，統合失調症の時間知覚における認知的方略の変化を明らかにしたことは精神疾患症状の発生メカニズムの解明に寄与するものであると考える．