Investigation of an index for hemodynamic instability during autologous blood donation.

2023 Fiscal Year Final Research Report

• Project/Area Number: 18K17489
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58060:Clinical nursing-related
• Research Institution: Tohoku Medical and Pharmaceutical University
• Principal Investigator: Kamakura Miho 東北医科薬科大学, 医学部, 非常勤研究員 (80700020)
• Project Period (FY): 2018-04-01 – 2024-03-31
• Keywords: 循環動態変動 / 自己血採血 / 自律神経活動 / 心拍変動

Outline of Final Research Achievements

This study aims to evaluate the relationships among cardiac autonomic nervous activity, hemodynamic instability, and the risk factor during autologous blood donation. Preoperative patients who were scheduled for autologous blood donation for intraoperative or postoperative use were enrolled. We recorded blood pressure and electrocardiographic data throughout autologous blood donation. The autonomic nervous activity was evaluated by using heart rate variability analyses. The glycoalbumin level correlated with the coefficient of variation (CV) of autonomic nervous activity, and CV of autonomic nervous activity was related to CV of blood pressure.

Free Research Field

臨床看護学、基礎看護学

Academic Significance and Societal Importance of the Research Achievements

心拍変動解析による自律神経活動の評価は非侵襲的であり、血圧や心拍数のみならずこれらの生理学的指標を加えたアセスメントを循環管理におけるケアに生かすことは、自己血採血を行う患者の安全確保、円滑な周術期管理を行うことに貢献できると考える。また、自己血採血のみならず、病院外での献血の場において安全に血液事業を進めることにも応用できる可能性がある。