2018 Fiscal Year Research-status Report
Establishment of a verification and validation framework for the computational fluid dynamics simulations of intracranial aneurysm hemodynamics
| Project/Area Number |
18K18356
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| Research Institution | Tohoku University |
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Principal Investigator |
TUPIN SIMON 東北大学, 流体科学研究所, 特任助教 (40816394)
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| Project Period (FY) |
2018-04-01 – 2020-03-31
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| Keywords | Intracranial Aneurysms / V&V / DNS / PIV |
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| Outline of Annual Research Achievements |
The first step of the project was to classify data from the hospital: intracranial aneurysm (IA) geometry, blood viscosity and blood flow waveform based on location, morphology, age and gender. This step is on-going and an averaging methodology was developed to compute geometrical models from a set of patient specific geometries.
The second step consisted in computational and experimental system and methods preparation. Direct Numerical Simulation (DNS) workflow was prepared to compute blood flow in generalized models using Newtonian and non-Newtonian viscosity models. In parallel, the experimental system to perform Particle Image Velocimetry (PIV) experiments was prepared and initial DNS/PIV comparison was done using an ideal model of internal carotid artery aneurysm.
Experimental systems and methods developed in this project were applied with success to other studies including the evaluation of blood and flush flow during endoscopy, evaluation of branch perfusion during AAA treatment with braided stents and the impact of vessel compliance on intra-aneurysmal flow.
Results were and are planed to be presented at several international and domestic conferences. Publications are also in preparation.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The project is progressing smoothly. Although the first step was not completed yet, the second step (DNS-PIV comparison) could be started using ideal geometry and silicone models already available.
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| Strategy for Future Research Activity |
The future work will be decomposed in the following points:
- Apply the developed averaging methods to patient specific aneurysm models in order to produce location dependent realistic models.
- Perform DNS simulations on those models and elucidate the difference between using Newtonian and non-Newtonian viscosity.
- Manufacture silicone replica of those models and perform PIV experiments and compare the results with the DNS simulations.
- Estimate the error resulting from using inappropriate viscosity models and boundary conditions.
- Publish the results and create an online database for researchers to verify and validate their simulations code/parameters.
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| Causes of Carryover |
Experimental setup was prepared using ideal silicone model already available in the laboratory. The manufacture of the averaged silicone models was then delayed as ideal models were sufficient for methods development and preliminary studies. Manufacture of these realistic geometrical models is planed for the first half of the second year.
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[Presentation] Perspective of development for PVA-H custom-made blood vessel models2018
Author(s)
Yasutomo Shimizu, Simon Tupin, Kaihong Yu, Ryota Nagano, Chihaya Kiyomitsu, Hiroshi Yoshida, Tadao Matsunaga, Junichi Kuzusako, Nobuhiro Kihara, Kazuto Takashima, Yoichi Haga and Makoto Ohta
Organizer
15th International Conference on Flow Dynamics (ICFD2018)
Int'l Joint Research / Invited
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