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2011 Fiscal Year Final Research Report

Promotion of muscle activities as the countermeasure for prevention of the deterioration of brain function

Research Project

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Project/Area Number 19100009
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Sports science
Research InstitutionOsaka University

Principal Investigator

OHIRA Yoshinobu  大阪大学, 医学系・研究科, 教授 (50185378)

Co-Investigator(Kenkyū-buntansha) NAKAI Naoya  大阪大学, 医学系・研究科, 准教授 (90324508)
KAWANO Fuminori  大阪大学, 医学系・研究科, 助教 (90346156)
NISHIMOTO Norihiro  和歌山県立医科大学, 医学部, 教授 (80273663)
SAKODA Saburou  大阪大学, 医学系・研究科, 教授 (00178625)
OHMI Shinobu  東京大学, 医科学研究所, 准教授 (20160046)
Project Period (FY) 2007 – 2011
Keywords筋活動 / 脳機能 / 感覚神経 / プロテオミクス / 筋再生
Research Abstract

Effects of antigravity muscle activity on the function and/ or protein expression in rat brain were studied. Since the muscle injury inhibits the physical activity, the study was also performed to investigate the suitable methods for promotion of regeneration of injured muscle. As the results, inhibition of hindlimb muscle activity by gravitational unloading caused detrimental effects on the normal growth and development of brain in new-born rats. Further, application of heat stress to injured muscles promoted the regeneration. In these muscles, cells expressing heat shock protein 72(HSP72) were observed in capillary vessels, not in muscle fibers. These cells were either bone marrow cells or neutrophils. The data indicated that HSP72 plays some indirect roles for stimulation of muscle regeneration. Heat-stress-specific changes in gene and protein expression were also observed.

  • Research Products

    (72 results)

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article (59 results) Book (13 results)

  • [Journal Article] HSP25 can modulate myofiber desmin cytoskeleton following the phosphorylation at Ser15 in rat soleus muscle2012

    • Author(s)
      Kawano, F., R. Fujita, N. Nakai, M. Terada, T. Ohira, and Y. Ohira
    • Journal Title

      J. Appl. Physiol

      Volume: 112 Pages: 176-186

  • [Journal Article] Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier2012

    • Author(s)
      Arima, Y., M. Harada, D. kamimura, J-H. Park, F. Kawano, F. E. Yull. T. Kawamoto, Y. Iwakura, U. A. K. Betz, G. Marquez, T. S. Blackwell, Y. Ohira, T. Hirano, and M. Murakami
    • Journal Title

      Cell

      Volume: 148 Pages: 447-457

  • [Journal Article] Biomedical analysis of rat body hair after hindlimb suspension for 14 days2012

    • Author(s)
      Terada, M., F. Kawano, N. Ishioka, A. Higashibata, H. J. Majima, T. Yamazaki, T. Watanabe-Asaka, M. Niihori, R. Nakano, S. Yamada, C. Mukai, and Y. Ohira
    • Journal Title

      Acta Astronautica

      Volume: 73 Pages: 23-29

  • [Journal Article] Effects of hindlimb unloading on neurogenesis in the hippocampus of newly weaned rats2012

    • Author(s)
      Nomura, S., K. Kami, F. Kawano, Y. Oke, N. Nakai, T. Ohira, R. Fujita, M. Terada, K. Imaizumi, and Y. Ohira
    • Journal Title

      Neurosci. Lett

      Volume: 509 Pages: 76-81

  • [Journal Article] Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission2012

    • Author(s)
      Sandona, D., J.-F. Desaphy, G. M. Camerino, E. Bianchini, S. Ciciliot, D. Danieli-Betto, G. Dobrowolny, S. Furlan, E. Germinario, K. Goto, M. Gutsmann, F. Kawano, N. Nakai, T. Ohira, Y. Ohno, A. Picard, M. Salanova, G. Schiffl, D. Blottner, A. Musaro, Y.
    • Journal Title

      PloS ONE

      Volume: 7 Pages: e33232

  • [Journal Article] The impact of long-term exposure to space environment on adult mammalian organisms : a study on mouse thyroid and testis2012

    • Author(s)
      Masini, M. A., E. Albi, C. Barmo, T. Bonfiglio, L. Bruni, L. Canesi, S. Cataldi, F. Curcio, M. D' Amora, I. Ferri, K. Goto, F. Kawano, R. Lazzarini, E. Loreti, N. Nakai, T. Ohira, Y. Ohira, S. Palmero, P. Prato, F. Ricci, L. Scarabelli, T. Shibaguchi, R.
    • Journal Title

      PloS ONE

      Volume: 7 Pages: e35418

  • [Journal Article] Responses of muscle mass, strength and gene expressions to long-term heat stress in healthy human subjects2011

    • Author(s)
      Goto, K., H. Oda, H. Kondo, M. Igaki, A. Suzuki, S. Tsuchiya, T. Murase, T. Hase, H. Fujiya, I. Matsumoto, H. Naito, T. Sugiura, Y. Ohira, and T. Yoshioka
    • Journal Title

      Eur. J. Appl. Physiol

      Volume: 111 Pages: 17-27

  • [Journal Article] Possible role of NF-. B signals in heat stress-associated increase in protein content of cultured C2C12 cells2011

    • Author(s)
      Ohno, Y., S. Yamada, T. Sugiura, Y. Ohira, T. Yoshioka, and K. Goto
    • Journal Title

      Cells Tissues Organs

      Volume: 194 Pages: 363-370

  • [Journal Article] Effects of creatine and its analog,.-guanidinopropionic acid, on the differentiation and nucleoli in myoblasts. Biosci2011

    • Author(s)
      Ohira, Y., Y. Matsuoka, F. Kawano, A. Ogura, Y. Higo, T. Ohira, M. Terada, Y. Oke, and N. Nakai
    • Journal Title

      Biotechnol. Biochem

      Volume: 75 Pages: 1085-1089

  • [Journal Article] Region-specific responses of adductor longus muscle to gravitational load-dependent activity in Wistar Hannover rats2011

    • Author(s)
      Ohira, T., X. D. Wang, M. Terada, F. Kawano, N. Nakai, A. Ogura, and Y. Ohira
    • Journal Title

      PLoS ONE

      Volume: 6 Pages: e21044

  • [Journal Article] Absence of heat shock transcription factor 1 retards the regrowth of atrophied soleus muscle in mice2011

    • Author(s)
      Yasuhara, K., Y. Ohno, A. Kojima, K. Uehara, M. Beppu, T. Sugiura, M. Fujimoto, A. Nakai, Y. Ohira, T. Yoshioka, and K. Goto
    • Journal Title

      J. Appl. Physiol

      Volume: 111 Pages: 1142-1149

  • [Journal Article] 3ヶ月の宇宙基地滞在がマウスの生理学的特性に及ぼす影響:宇宙実験のコントロールとしての地上シミュレーション実験2011

    • Author(s)
      大平充宣、中井直也、河野史倫、大平宇志、芝口翼、藤田諒、後藤勝正、石原昭彦、大石康晴、山崎将生、向井千秋、寺田昌弘、山下雅道、宇佐美眞一、奥野誠、落合俊昌、行徳淳一郎
    • Journal Title

      Space Utiliz. Res

      Volume: 27 Pages: 122-123

  • [Journal Article] 哺乳類小動物を用いた宇宙生物学実験2011

    • Author(s)
      山崎将生、大平充宣、奥野誠、石原昭彦、清水強、粂井康宏、伊藤康宏、野村裕子、高林彰、大西武雄、片平清昭、矢野昭起、中野完、山下雅道
    • Journal Title

      Space Utiliz. Res

      Volume: 27 Pages: 124-126

  • [Journal Article] 宇宙環境での疾病と健康管理-2010年(第1年度)研究チーム活動報告-2011

    • Author(s)
      石原昭彦、津田謹輔、神埼素樹、永友文子、藤野英己、平田総一郎、三浦靖史、村上慎一郎、近藤浩代、武田功、大平充宣
    • Journal Title

      Space Utiliz. Res

      Volume: 27 Pages: 142-144

  • [Journal Article] 尾部懸垂の精子形成における影響2011

    • Author(s)
      奥野誠、向井千夏、大平充宣
    • Journal Title

      Space Utiliz. Res

      Volume: 27 Pages: 203-204

  • [Journal Article] 健康の維持・増進を目指した運動処方のヒトおよびラットにおける再検討2011

    • Author(s)
      大平充宣、中井直也、岡部洋興、陳全寿
    • Journal Title

      デサントスポーツ科学

      Volume: 32 Pages: 11-18

  • [Journal Article] 筋機能からみた萎縮と肥大のメカニズム2011

    • Author(s)
      後藤勝正、大平充宣
    • Journal Title

      体育の科学別冊61

      Volume: 12 Pages: 900-906

  • [Journal Article] Myonucleus-related properties in soleus muscle fibers of mdx mice2010

    • Author(s)
      Terada, M., Y. B. Lan. F. Kawano, T. Ohira, Y. Higo, N. Nakai, K. Imaizumi, A. Ogura, N. Nishimoto, Y. Adachi, and Y. Ohira
    • Journal Title

      Cells Tissues Organs

      Volume: 191 Pages: 248-259

  • [Journal Article] Role(s) of gravitational loading during developing period on the growth of rat soleus muscle fibers2010

    • Author(s)
      Kawano, F., K. Goto, X. D. Wang, M. Terada, T. Ohira, N. Nakai, T. Yoshioka, and Y. Ohira
    • Journal Title

      J. Appl. Physiol

      Volume: 108 Pages: 676-685

  • [Journal Article] A possible role of NF-. B and HSP72 in skeletal muscle hypertrophy induced by heat stress in rats2010

    • Author(s)
      Ohno, Y., S. Yamada, T. Sugiura, Y. Ohira, T. Yoshioka, and K. Goto
    • Journal Title

      Gen. Physiol. Biophys

      Volume: 29 Pages: 234-242

  • [Journal Article] Role(s) of mechanical load and satellite cells in the regulation of the size of soleus muscle fiber in rats2010

    • Author(s)
      Ohira, Y., F. Kawano, X. D. Wang, N. Nakai, T. Ohira, H. Okabe, H. Naito, and K. Goto
    • Journal Title

      Biol. Sci. Space

      Volume: 24 Pages: 135-144

  • [Journal Article] Mechanical stretch activates signaling events for protein translation initiation and elongation in C2C12 myoblasts2010

    • Author(s)
      Nakai, N., F. Kawano, Y. Oke, S. Nomura, T. Ohira, R. Fujita, and Y. Ohira
    • Journal Title

      Mol. Cells

      Volume: 30 Pages: 513-518

  • [Journal Article] 体位変換による血液分布の変化が運動能力に及ぼす影響:自転車エルゴメーター運動中の制限因子の検討2010

    • Author(s)
      川畑哲也、岡部洋興、大平宇志、河野史倫、内藤久士、大平充宣
    • Journal Title

      宇宙航空環境医学

      Volume: 47 Pages: 15-22

  • [Journal Article] 発育期の脚運動がラット脳の発育・発達に及ぼす影響2010

    • Author(s)
      大平充宣、野村幸子、尾家慶彦、大平宇志、河野史倫、藤田諒、中井直也、今泉和彦
    • Journal Title

      早稲田大学人間科学学術院「人間科学研究」

      Volume: 第23巻第1号補遺号 Pages: 127

  • [Journal Article] Possible Utilization of Gerbils for Spaceflight Experiment2009

    • Author(s)
      Ohira, Y., Y. Nakajima, N. Nakai, F. Kawano, M. Terada, T. Ohira, K. Goto, S. Nagaoka, M. Yamasaki, M., Ishihara, A. and Oishi, Y
    • Journal Title

      Space Utiliz. Res

      Volume: 25 Pages: 135-136

  • [Journal Article] Effects of hindlimb unloading at early postnatal growth on cell body size in spinal motoneurons innervating soleus muscle of rats2009

    • Author(s)
      Nagatomo, F., A. Ishihara, and Y. Ohira
    • Journal Title

      Int' l. J. Develop. Neurosci

      Volume: 27 Pages: 21-26

  • [Journal Article] Neural and/ or mechanical responses of adductor longus muscle to exposure to microgravity in Wistar Hannover rats2009

    • Author(s)
      Ohira, T., M. Terada, F. Kawano, N. Nakai, K. Ohira, T. Ochiai, J. Gyotoku, A. Ogura, and Y. Ohira
    • Journal Title

      Jpn. J. Aerosp. Environ. Med

      Volume: 46(2) Pages: 21-28

  • [Journal Article] Gravitational unloading inhibits the regenerative potential of atrophied soleus muscle in mice2009

    • Author(s)
      Matsuba, Y., K. Goto, S. Morioka, T. Naito, T. Akema, N. Hashimoto, T. Sugiura, Y. Ohira, M. Beppu, and T. Yoshioka
    • Journal Title

      Acta Physiol

      Volume: 196 Pages: 329-339

  • [Journal Article] Administration of granulocyte colony-stimulating factor facilitates the regenerative process of injured mice skeletal muscle via the activation of Akt/ GSK3αβsignals2009

    • Author(s)
      Naito, T., K. Goto, S. Morioka, Y. Matuba, T. Akema, T. Sugiura, Y. Ohira, M. Beppu, and T. Yoshioka
    • Journal Title

      Europ. J. Appl. Physiol

      Volume: 105 Pages: 643-651

  • [Journal Article] Heat stress increases myonuclear number and fiber size via satellite cell activation in rat regenerating soleus fibers2009

    • Author(s)
      Oishi, Y., M. Hayashida, S. Tsukiashi, K. Taniguchi, K. Kami, R. R. Roy, and Y. Ohira
    • Journal Title

      J. Appl. Physiol

      Volume: 107 Pages: 1612-1621

  • [Journal Article] Investigation of the mechanism responsible for muscle atrophy and countermeasures in microgravity environment : Role(s) of mechanical load and/ or satellite cells2008

    • Author(s)
      Ohira, Y., X. D. Wang, M. Terada, F. Kawano, Y. Matsuoka, Y. Higo, T. Ohira, A. Kojima, K. Goto, and T. Yoshioka
    • Journal Title

      Proceedings of the 1st International Space Medicine Symposium 2007 in Sapporo

      Pages: 91-96

  • [Journal Article] Cellular adaptations in soleus muscle during recovery after hindlimb unloading2008

    • Author(s)
      Oishi, Y., T. Ogata, K. Yamamoto, M. Terada, T. Ohira, Y. Ohira, K. Taniguchi, and R. R. Roy
    • Journal Title

      Acta Physiol

      Volume: 192 Pages: 381-395

  • [Journal Article] Effects of loading or unloading on the regenerative potential of injured skeletal muscle in mice2008

    • Author(s)
      Goto, K., Y. Matsuba, Y. Ohno, T. Sugiura, N. Hashimoto, Y. Ohira, and T. Yoshioka
    • Journal Title

      J. Gravit. Physiol

      Volume: 15 Pages: 83-84

  • [Journal Article] Garavitational loading stimulates adhesion of satellite cells and myonuclear accretion during fiber growth in rat soleus muscle2008

    • Author(s)
      Kawano, F., X. D. Wang, N. Nakai, Y. Higo, M. Terada, T. Ohira, I. Nonaka, and Y. Ohira
    • Journal Title

      J. Gravit. Physiol

      Volume: 15 Pages: 85-86

  • [Journal Article] Role(s) of gravitational loading on the growth-related transformation of fiber phenotype in rat soleus2008

    • Author(s)
      Ohira, Y., F. Kawano, K. Goto, M. Terada, T. Ohira, N. Nakai, Y. Higo, and T. Yoshioka
    • Journal Title

      J. Gravit. Physiol

      Volume: 15 Pages: 93-94

  • [Journal Article] Responses of electromyogram activity in adductor longus muscle of rats to the altered gravity levels2008

    • Author(s)
      Ohira, T., X. D. Wang, M. Terada, F. Kawano, Y. Higo, N. Nakai, T. Ochiai, J. Gyotoku, N. Nishimoto, A. Ogura, and Y. Ohira
    • Journal Title

      J. Gravit. Physiol

      Volume: 15 Pages: 95-96

  • [Journal Article] Effects of mechanical overloading on the properties of soleus muscle fibers, with or without damage, in mdx and wild type mice2008

    • Author(s)
      Terada, M., F. Kawano, T. Ohira, Y. Oke, N. Nakai, and Y. Ohira
    • Journal Title

      J. Gravit. Physiol

      Volume: 15 Pages: 97-98

  • [Journal Article] Effects of peroxisome proliferator-activated receptor.(PPAR.) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells2008

    • Author(s)
      Nakai, N., F. Kawano, M. Terada, Y. Oke, T. Ohira, and Y. Ohira
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1780 Pages: 1101-1105

  • [Journal Article] Essential role of satellite cells in the growth of rat soleus muscle fibers2008

    • Author(s)
      Kawano, F., Y. Takeno, N. Nakai, Y. Higo, M. Terada, T. Ohira, I. Nonaka, and Y. Ohira
    • Journal Title

      Am. J. Physiol. Cell Physiol

      Volume: 295 Pages: C458-C467

  • [Journal Article] Gene expression levels of heat shock proteins in soleus and plantaris muscles of rats after hindlimb suspension or spaceflight2008

    • Author(s)
      Ishihara, A., H. Fujino, F. Nagatomo, I. Takeda, and Y. Ohira
    • Journal Title

      J. Physiol. Sci

      Volume: 58 Pages: 413-417

  • [Journal Article] Functional overloading facilitates the regeneration of injured soleus muscles in mice2008

    • Author(s)
      Morioka, S., K. Goto, A. Kojima, T. Naito, Y. Matsuba, T. Akema, H. Fujiya, T. Sugiura, Y. Ohira, M. Beppu, H. Aoki, and T. Yoshioka
    • Journal Title

      J. Physiol. Sci

      Volume: 58 Pages: 397-404

  • [Journal Article] Heat-stress facilitates the regeneration of injured skeletal muscle in rats2007

    • Author(s)
      Kojima, A., K. Goto, S. Morioka, T. Naito, T. Akema, H. Fujiya, T. Sugiura, Y. Ohira, M. Beppu, H. Aoki, and T. Yoshioka
    • Journal Title

      J. Orthopaed. Sci

      Volume: 12 Pages: 74-82

  • [Journal Article] Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period2007

    • Author(s)
      Watanabe, S., Y. Hitomi, F. Kawano, Y. Ohira, T. Kizaki, N. Nakano, T. Sakurai, T. Izawa, K. Suzuki, M. Sudoh, R. R. Roy, and H. Ohno
    • Journal Title

      Acta Astronautica

      Volume: 60 Pages: 889-898

  • [Journal Article] Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells2007

    • Author(s)
      Goto, K., A. Kojima, S. Morioka, T. Naito, T. Akema, Y. Matsuba, H. Fujiya, T. Sugiura, Y. Ohira, and T. Yoshioka
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 358 Pages: 331-335

  • [Journal Article] Skeletal muscle hypertrophy induced by low-intensity exercise with heat-stress in healthy human subjects2007

    • Author(s)
      Goto, K., H. Oda, S. Morioka, T. Naito, T. Akema, H. Kato, H. Fujiya, Y. Nakajima, T. Sugiura, Y. Ohira, and T. Yoshioka
    • Journal Title

      Jpn. J. Aerosp. Environ. Med

      Volume: 44 Pages: 13-18

  • [Journal Article] Effects of mechanical and/ or neural stimuli on the properties of soleus muscle fibers in mdx mice2007

    • Author(s)
      Lan, Y. B., M. Terada, Y. Higo, F. Kawano, Y. Matsuoka, X. D. Wang, N. Nakai, and Y. Ohira
    • Journal Title

      Jpn. J. Aerosp. Environ. Med

      Volume: 44 Pages: 19-29

  • [Journal Article] Role(s) of nucleoli and phosphorylation of ribosomal protein S6 and/ or HSP27 in the regulation of muscle mass2007

    • Author(s)
      Kawano, F., Y. Matsuoka, Y. Oke, Y. Higo, M. Terada, X. D. Wang, N. Nakai, H. Fukuda, S. Imajoh-Ohmi, and Y. Ohira
    • Journal Title

      Am. J. Physiol. Cell Physiol

      Volume: 293 Pages: C35-C44

  • [Journal Article] Effects of functional overloading on the regenerative potential of injured skeletal muscles in mice2007

    • Author(s)
      Goto, K., S. Morioka, T. Naito, T. Akema, Y. Matsuba, T. Sugiura, Y. Ohira, and T. Yoshioka
    • Journal Title

      J. Gravit. Physiol

      Volume: 14 Pages: 101-102

  • [Journal Article] Cell size and oxidative enzyme activity of rat biceps brachii and triceps brachii muscles2007

    • Author(s)
      Matsumoto, A., F. Nagatomo, A. Mori, Y. Ohira, and A. Ishihara
    • Journal Title

      J. Physiol. Sci

      Volume: 57 Pages: 311-316

  • [Journal Article] Responses of vastus lateralis muscle fibers to cycling training with different loading parameters in human2007

    • Author(s)
      Terada, M., E. Lyubaeva, T. Ohira, A. Netreba, F. Kawano, H. Okabe, T. Aoyama, K. Imaizumi, O. Vinogradova, and Y. Ohira
    • Journal Title

      Jpn. J. Aerospace Environ. Med

      Volume: 44 Pages: 59-64

  • [Journal Article] Effects of hyperbaric exposure with high oxygen concentration on the physical activity of developing rats2007

    • Author(s)
      Matsumoto, A., T. Okiura, F. Morimatsu, Y. Ohira, and A. Ishihara
    • Journal Title

      Dev. Neurosci

      Volume: 29 Pages: 452-459

  • [Journal Article] Evaluation of gene, protein and neurotrophin expression in the brain of mice exposed to space environment for 91 days

    • Author(s)
      Santucci, D., F. Kawano, T. Ohira, M. Terada, N. Nakai, N. Francia, E. Alleva, L. Aloe, T. Ochiai, R. Cancedda, K. Goto, and Y. Ohira
    • Journal Title

      PLoS ONE

      Volume: (in press)

  • [Journal Article] Effects of inhibited antigravity muscle activity on the expression of hippocampal proteins in growing rats

    • Author(s)
      Oke, Y., F. Kawano, S. Nomura, T. Ohira, R. Fujita, M. Terada, T. Shibaguchi, N. Nakai, and Y. Ohira
    • Journal Title

      Jpn. J. Aerosp. Envion. Med

      Volume: (in press)

  • [Journal Article] Responses of HSC70 expression in diencephalon to iron deficiency anemia in rats

    • Author(s)
      Kawano, F., Y. Oke, S. Nomura, R. Fujita, T. Ohira, N. Nakai, and Y. Ohira
    • Journal Title

      J. Physiol. Sci

      Volume: (in press)

  • [Journal Article] Effects of mechanical over-loading on the properties of soleus muscle fibers, with or without damage, in wild type and mdx mice

    • Author(s)
      Terada, M., F. Kawano, T. Ohira, N. Nakai, N. Nishimoto, and Y. Ohira
    • Journal Title

      PLoS ONE

      Volume: (in press)

  • [Journal Article] Neuromuscular responses to spaceflight

    • Author(s)
      Ohira, Y., F. Kawano, T. Ohira, T. Ohira, H. Okabe, H. Naito, K. Goto, and A. Ishihara
    • Journal Title

      J. Gravit. Physiol.(Review)

      Volume: (in press)

  • [Journal Article] Regulation of soleus muscle properties by mechanical stress and/ or neural acrivity

    • Author(s)
      Kawano, F., N. Nakai, and Y. Ohira
    • Journal Title

      J. Phys. Fit. Sports Med.(Review)

      Volume: (in press)

  • [Journal Article] Some aspects of heat stress on the plasticity of skeletal muscle cells

    • Author(s)
      Goto, K., Y. Ohno, A. Goto, A. Ikuta, M. Suzuki, T. Ohira, N. Tsuchiya, S. Nishizawa, T. Koya, T. Egawa, T. Sugiura, Y. Ohira, and T. Yoshioka, T
    • Journal Title

      J. Phys. Fit. Sports Med.(Review)

      Volume: (in press)

  • [Journal Article] Control of muscle protein synthesis in response to exercise and amino acids

    • Author(s)
      Nakai, N., F. Kawano, and Y. Ohira
    • Journal Title

      J. Phys. Fit. Sports Med.(Review)

      Volume: (in press)

  • [Book] 運動・加齢に対する骨格筋の適応2010

    • Author(s)
      上勝也、大平充宣
    • Total Pages
      25-29
    • Publisher
      The Bone
  • [Book] 免疫力を高める運動とは?運動と免疫2009

    • Author(s)
      上勝也、大平充宣
    • Total Pages
      400-405
    • Publisher
      ナップ
  • [Book] 運動と無重力環境と免疫2009

    • Author(s)
      大平宇志、西本憲弘、大平充宣
    • Total Pages
      377-381
    • Publisher
      ナップ
  • [Book] The role of branched-chain amino acids in energy metabolism and protein synthesis in skeletal muscle. In" Muscle Cell Physiology"2009

    • Author(s)
      Nakai, N. and Y. Ohira
    • Total Pages
      3-14
    • Publisher
      Ed. by Y. Ohira, Osaka University Press
  • [Book] Metabolic modulation of muscle properties : Role(s) of high-energy phosphates. In" Muscle Cell Physiology"2009

    • Author(s)
      Ohira, Y
    • Total Pages
      15-28
    • Publisher
      Ed. by Y. Ohira, Osaka University Press
  • [Book] Role of mechanical stress and neural activity in the regulation of antigravity muscle. In" Muscle Cell Physiology"2009

    • Author(s)
      Kawano, F., N. Nakai, and Y. Ohira
    • Total Pages
      29-40
    • Publisher
      Ed. by Y. Ohira, Osaka University Press
  • [Book] A hypertrophic stimulus for skeletal muscles. In" Muscle Cell Physiology"2009

    • Author(s)
      Goto, K., Y. Ohira, and T. Yoshioka. Heat stress
    • Total Pages
      41-50
    • Publisher
      Ed. by Y. Ohira, Osaka University Press
  • [Book] From intracellular signaling pathways to behavior. In" Muscle Cell Physiology"2009

    • Author(s)
      Kami, K. and Y. Ohira. Skeletal muscle regeneration
    • Total Pages
      71-83
    • Publisher
      Ed. by Y. Ohira, Osaka University Press
  • [Book] 血液。運動療法と運動処方。身体活動・運動支援を効果的に進めるための知識と技術。第2版2008

    • Author(s)
      大平充宣
    • Total Pages
      365-369
    • Publisher
      文光堂
  • [Book] 宇宙飛行士の体力。体力とはなにか-運動処方のその前に.長澤純一(編)2007

    • Author(s)
      大平充宣
    • Total Pages
      119-126
    • Publisher
      ナップ
  • [Book] 重力と気圧:宇宙。「環境生理学」、本間研一・彼末一之・編2007

    • Author(s)
      大平充宣、関口千春、石井正則、石原昭彦
    • Total Pages
      245-260
    • Publisher
      北海道大学出版会
  • [Book] 宇宙環境への適応とその防止策。「スポーツの科学」2007

    • Author(s)
      大平充宣
    • Total Pages
      142-155
    • Publisher
      財団法人日本学術協力財団
  • [Book] かけがえのない水の惑星・地球,人体には水が必須!,水・その不思議な世界:私たちの星を守るために2007

    • Author(s)
      大平充宣
    • Total Pages
      (pp. 10-12)(pp. 53-55)
    • Publisher
      高知新聞社

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Published: 2013-07-31  

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