2011 Fiscal Year Final Research Report
The genome-wide study on the regulation of muscle differentiation in fish
| Project/Area Number |
19108003
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| Research Category |
Grant-in-Aid for Scientific Research (S)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fisheries chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
WATABE Shugo 東京大学, 大学院・農学生命科学研究科, 教授 (40111489)
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| Co-Investigator(Kenkyū-buntansha) |
KINOSHITA Shigeharu 東京大学, 大学院・農学生命科学研究科, 助教 (40401179)
OCHIAI YOSHIHIRO 東京大学, 大学院・農学生命科学研究科, 准教授 (50160891)
KANEKO TOYOJI 東京大学, 大学院・農学生命科学研究科, 教授 (70221190)
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| Co-Investigator(Renkei-kenkyūsha) |
OCHIAI Yoshihiro 東京大学, 大学院・農学生命科学研究科, 准教授 (50160891)
KANEKO Toyoji 東京大学, 大学院・農学生命科学研究科, 教授 (70221190)
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| Project Period (FY) |
2007 – 2011
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| Keywords | 水産学 / 魚類 / ゲノム / 発生・分化 / 筋肉 / ミオシン |
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| Research Abstract |
This study focused on myosin heavy chain gene(MYH), which defines muscle properties. We showed that diverse expression of MYHs is closely related to structures and functions of the muscle in fish, revealing a part of transcriptional network involved in the regulation of MYH expression. These findings are expected to contribute to fisheries industry by, for example, the improvement of meat quality and the establishment of fast growth fish strains, based on the molecular mechanisms involved in muscle differentiation and growth.
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