Molecular basis of Rac GTPase in plant innate immunity

2009 Fiscal Year Self-evaluation Report

• Project/Area Number: 19108005
• Research Category: Grant-in-Aid for Scientific Research (S)
• Allocation Type: Single-year Grants
• Research Field: Applied molecular and cellular biology
• Research Institution: Nara Institute of Science and Technology
• Principal Investigator: SHIMAMOTO Ko Nara Institute of Science and Technology, バイオサイエンス研究科, 教授 (10263427)
• Project Period (FY): 2007 – 2011
• Keywords: 植物免疫

Research Abstract

本研究課題では、植物自然免疫機構の中枢であると言える、病原体認識機構および信号伝達の分子機構をタンパク質間相互作用から得られた耐病性関連タンパク質の分子ネットワークの解析を通じて明らかにする。

Research Products

• [Journal Article] Hop/Sti1 and HSP90 are involved in maturation and transport of a PAMP receptor in rice innate immunity (2010)
  • Author(s): Chen, L., Hamada, S., Fujiwara, M., Zhu, T., Thao, N. P, Wong, H. L., Krishna, P., Ueda, T., Kaku, H., Shibuya, N., Kawasaki, T., Shimamoto, K
  • Journal Title: Cell Host Microbe 7 Pages: 185-96
  • Peer Reviewed
• [Journal Article] RACK1 functions in rice innate immunity by interacting with the Rac1 immune complex (2008)
  • Author(s): Nakashima, A., Chen, L., Thao, N. P., Fujiwara, M., Wong, H. L., Kuwano, M., Umemura, K., Shirasu, K., Kawasaki, T., Shimamoto, K.
  • Journal Title: Plant Cell 20 Pages: 2265-2279
  • Peer Reviewed
• [Journal Article] RAR1 and HSP90 form a complex with Rac/Rop GTPase and function in innate immune responses in rice (2007)
  • Author(s): Thao, N. P., Chen, L., Nakashima, A., Hara, S., Umemura, K., Takahashi, A, Shirasu, K., Kawasaki, T., Shimamoto, K.
  • Journal Title: Plant Cell 19 Pages: 4035-4045
  • Peer Reviewed
• [Journal Article] Activation of a Rac GTPase by the NLR Family Disease Resistance Protein Pit Plays a Critical Role in Rice Inna…te Immunity
  • Author(s): Kawano, Y., Akamatsu, A., Hayashi, K., Housen, Y., Okuda, J., Nakashima, A., Takahashi, H., Yoshida, H., Hann Ling Wong, Kawasaki, T., Shimamoto, K.
  • Journal Title: Cell Host Microbe (in Press)
  • Peer Reviewed
• [Presentation] OsRac1 GTPase is a key regulator of PTI and ETI in rice (2009)
  • Author(s): Shimamoto, K.
  • Organizer: XIV International Congress on Molecular Plant-Microbe Interactions
  • Place of Presentation: カナダ
  • Year and Date: 20090000
• [Book] Advances in Genetics, Genomics and Control of Rice Blast Disease.(G.L. Wang et al. eds., Rice guanine nucleotide exchange factors for small GTPase OsRac1 involved in innate immunity of rice.) (2008)
  • Author(s): Kawasaki, T., Imai, K., Wong, H. L., Kawano, Y., Nishide, K., Okuda, J., Shimamoto, K., G. L. Wang, et al.
  • Total Pages: 179-184
  • Publisher: Springer