2010 Fiscal Year Final Research Report
Functional division in the prefrontal cortex during goal-directed behavior utilizing behavioral rules
| Project/Area Number |
19200027
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Neuroscience in general
|
|---|
| Research Institution | The Institute of Physical and Chemical Research |
|---|
Principal Investigator |
TANAKA Keiji The Institute of Physical and Chemical Research, 認知機能表現研究チーム, チームリーダー (00221391)
|
|---|
| Project Period (FY) |
2007 – 2010
|
| Keywords | マカク属サル / 前頭前野 / 目的指向的行動 / 行為選択ルール / ウィスコンシンカード分類課題 / 前頭眼窩皮質 / 前帯状溝皮質 / 前頭前野背外側部 |
|---|
| Research Abstract |
To achieve goals in complex environment, one has to use a behavioral rule matching the goal and the current environmental situation. To clarify mechanisms of such goal-directed behavior, we have trained macaque monkeys with an analog of Wisconsin Card Sorting Test, and conducted lesion-behavioral and single-cell recording experiments. We obtained results suggesting that the dorsolateral, orbitofrontal and anterior cingulate sulcus regions of the prefrontal cortex play different elementary functional roles in the performance of the rule-based goal-directed behavior.
|
