2010 Fiscal Year Final Research Report
Stress Detection in Bone tissue with Hierarchical Composite Structure
| Project/Area Number |
19200035
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Hokkaido University |
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Principal Investigator |
TADANO Shigeru Hokkaido University, 大学院・工学研究院, 教授 (50175444)
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| Co-Investigator(Kenkyū-buntansha) |
SASAKI Naoki 北海道大学, 大学院・理学研究院, 教授 (40142202)
SHIRATO Hiroki 北海道大学, 大学院・医学研究科, 教授 (20187537)
HURUSAKA Michihiro 北海道大学, 大学院・工学研究院, 教授 (60156966)
TODOH Masahiro 北海道大学, 大学院・工学研究院, 准教授 (10314402)
FUJISAKI Kazuhiro 北海道大学, 大学院・工学研究院, 助教 (90435678)
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| Project Period (FY) |
2007 – 2010
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| Keywords | バイオメカニクス / 生体骨組織 / 応力検出 / X線回折 / 皮質骨 / ハイドロキシアパタイト / 結晶配向性 |
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| Research Abstract |
Bone shows a hierarchical structure from a nano scale of hydroxyapatite crystal and collagen molecular to a macro scale of cortical and cancellous bone. This work proposed a new method of detecting stress of tissue level using the information of HAp crystal deformation. X-ray diffraction (XRD) experimental procedure was developed to measure the characteristics of hierarchical structure. Some structural parameters were introduced to represent these characteristics. Also, the XRD method was applied to detect residual stress in bone, and the stress was observed at various regions in animal extremities.
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Research Products
(39 results)
