2009 Fiscal Year Final Research Report
Development of method for evaluating the consistency between network model in the cell and the molecular measured data
| Project/Area Number |
19201039
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
基礎ゲノム科学
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
HORIMOTO Katsuhisa National Institute of Advanced Industrial Science and Technology, 生命情報工学研究センター, 研究チーム長 (40238803)
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| Co-Investigator(Kenkyū-buntansha) |
ABURATANI Sachiyo 独立行政法人産業技術総合研究所, 生命情報工学研究センター, 研究員 (10361627)
TOMINAGA Daisuke 独立行政法人産業技術総合研究所, 生命情報工学研究センター, 研究員 (20357578)
ANAI Hirokazu 株式会社富士通研究所, Tコア研究所, 研究員 (20417520)
YOSHIDA Hiroshi 九州大学, 数理科学研究院, 特任助教授 (60401262)
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| Project Period (FY) |
2007 – 2009
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| Keywords | システム生物学 / ネットワーク解析 / グラフィカル・モデル / 記号計算 |
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| Research Abstract |
We have developed two methods for evaluating the consistency between the given network structures and the measured data of constituent molecules, based on the statistical and symbolic-numeric approaches. By using these methods, the active networks can be detected under a particular condition, and furthermore, the changes of network structures can be traced, depending on the environmental changes.
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