2010 Fiscal Year Final Research Report
Development and Evaluation of Integron Gene Cassette Metagenome Analysis
| Project/Area Number |
19201041
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied genomics
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
MARUYAMA Akihiko National Institute of Advanced Industrial Science and Technology, 生物プロセス研究部門, 研究グループ付 (30202336)
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| Co-Investigator(Kenkyū-buntansha) |
YASURO Kurusu 茨城大学, 農学部, 教授 (60272118)
HIDEYOSHI Yoshioka 独立行政法人産業技術総合研究所, 地圏資源環境研究部門, 研究員 (30415765)
HIROYUKI Fuse 独立行政法人産業技術総合研究所, 生物機能工学研究部門, 主任研究員 (10358103)
SATOSHI Suyama 独立行政法人産業技術総合研究所, 生物機能工学研究部門, 研究員 (10358103)
YASUO Mitani 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 研究員 (10358103)
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| Research Collaborator |
ELSAIED Hosam 独立行政法人産業技術総合研究所, 生物プロセス研究部門・1号契約, 職員
STOKES Halord シドニー工科大学, 教授
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| Project Period (FY) |
2007 – 2010
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| Keywords | 微生物 / 遺伝子 / メタゲノム / インテグロン / 環境適応 / 極限環境 / IODP / 海洋 |
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| Research Abstract |
This project aimed to study the mobile DNA element, integrons, and associated gene cassettes, for the first time, in extreme marine environments. Novel and diverse integron structures and environment- adaptive gene cassettes have been recovered. This project had three main achievements. First, it introduced new methodology for recovery of integrons from environmental metagenomes. Second, it extended our understanding to the contribution of integrons in the adaptation of bacteria to extreme marine conditions. Third, it provided us with several novel adaptive and metabolic genes that have several biotechnological applications.
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