2010 Fiscal Year Final Research Report
Analysis of molecular mechanisms of anti-viral response in insects
| Project/Area Number |
19208006
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Applied entomology
|
|---|
| Research Institution | Nagoya University |
|---|
Principal Investigator |
KOBAYASHI Michihiro Nagoya University, 生命農学研究科, 教授 (60111837)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
IKEDA Motoko 名古屋大学, 大学院・生命農学研究科, 准教授 (20262892)
NIIMI Teruyuki 名古屋大学, 大学院・生命農学研究科, 助教 (00293712)
|
|---|
| Project Period (FY) |
2007 – 2010
|
| Keywords | 抗ウイルス応答 / アポトーシス / 全タンパク質合成停止 / 昆虫 / バキュロウイルス / 核多角体病ウイルス |
|---|
| Research Abstract |
Apoptosis and global protein synthesis shutdown (shutdown of protein synthesis in both host cells and viruses) serve as major anti-viral defense mechanisms in the insects, which lack adaptive immunity. To elucidate molecular mechanisms that underlie apoptosis and global protein synthesis shutdown induced upon virus infection, we have conducted experiments in cultured insect cells infected with nucleopolyhedroviruses (NPVs). We identified and characterized several viral and cellular genes that are involved in the regulation of apoptosis and global protein synthesis shutdown.
|
-
-
-
-
-
[Journal Article] Comparative studies of a lepidopteran baculovirus-specific protein FP25K : Development of a novel BmNPV-based vector with a modified fp25K.2010
Author(s)
Nakanishi, T., Goto, C., Kobayashi, M., Kang, W., Suzuki, T., Dohmae, N., Matsumoto, S., Shimada, T., Katsuma, S.
-
Journal Title
J.Vrol. 84
Pages: 5191-5200
Peer Reviewed
-
-
-
-
-
[Journal Article] Cloning and comparative characterization of nucleopolyhedroviruses isolated from African bollworm, Helicoverpa armigera (Lepidoptera : Noctuidae) in different geographic regions.2007
Author(s)
Ogembo, J. G., Chaeychomsri, S., Kamiya, K., Ishikawa, H., Katou, Y., Ikeda. M., Kobayashi, M.
-
Journal Title
J.Insect Biotechnol.Sericol. 76
Pages: 39-49
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Development of a Helicoverpa armigera nucleopolyhedrovirus isolated from Kenya as biological control agent.2008
Author(s)
Ogembo, J.G., Caoili, B.L., Chaeychomsri, S.. Kamiya, K., Ishikawa, H., Karen, Y., Ikeda M., Kobayashi M.
Organizer
Asia-Pacific Congress of Sericulture and Insect Biotechnology.
Place of Presentation
Nagoya.
Year and Date
20080321-20080322
-
-
-
-
-
