2009 Fiscal Year Final Research Report
Development of a flat-bed-type chemical image scanner and its application to bioimaging
| Project/Area Number |
19350036
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Tohoku University |
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Principal Investigator |
YOSHINOBU Tatsuo Tohoku University, 大学院・医工学研究科, 教授 (30243265)
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| Co-Investigator(Kenkyū-buntansha) |
KANOH Shin'ichiro 東北大学, 大学院・工学研究科, 助教 (00282103)
MIYAMOTO Ko-ichiro 東北大学, 大学院・工学研究科, 助教 (70447142)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 化学センサー |
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| Research Abstract |
In this study, a flat-bed-type chemical image scanner was developed, which was capable of visualizing the distribution of specific ions or molecules in the specimen placed on the sensing surface. In the developed system, a large-area sensor was scanned by a plurality of light sources in parallel, which resulted in great reduction of measurement time in comparison to the conventional chemical imaging sensor system. A new measurement mode was proposed, in which the ion concentration was determined by measuring the phase of the photocurrent, and its insensitivity to fluctuation of light intensity and defects in the sensor plate was demonstrated.
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