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2009 Fiscal Year Final Research Report

Multimodal imaging system for biological function measurements by using diffusion light

Research Project

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Project/Area Number 19360035
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied optics/Quantum optical engineering
Research InstitutionKeio University

Principal Investigator

OKADA Eiji  Keio University, 理工学部, 教授 (40221840)

Co-Investigator(Kenkyū-buntansha) KANNARI Fumihiko  慶應義塾大学, 理工学部, 教授 (40204804)
NAKANO Nobuhiko  慶應義塾大学, 理工学部, 准教授 (40286638)
Project Period (FY) 2007 – 2009
Keywords応用光学・量子光工学 / 光・画像計測工学 / 生物・生体工学 / シミュレーション工学 / 生体医用光工学
Research Abstract

A multimodal system for the brain-function measurement using near-infrared light is investigated to improve the spatial resolution and accuracy of brain-function images. The novel algorithm for image reconstruction using a virtual head phantom is proposed. The 3D-structure of the virtual head phantom is based upon MRI scan of an adult head. The proposed system is evaluated by simulations using the virtual head phantom and experiments. The brain-function images measured by the system using double-density probe arrangement are effectively improved by the image reconstruction algorithm using the virtual phantom.

  • Research Products

    (8 results)

All 2009 2008 2007

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (4 results) Book (1 results)

  • [Journal Article] Validation of practical diffusion approximation for virtual near infrared spectroscopy using a digital head phantom2009

    • Author(s)
      Yosuke Oki、Hiroshi Kawaguchi、Eiji Okada
    • Journal Title

      Optical Review 16巻

      Pages: 153-159

    • Peer Reviewed
  • [Journal Article] Theoretical analysis of crosstalk between oxygenated and deoxygenated haemoglobin in focal brain-activation measurements by near-infrared topography2008

    • Author(s)
      Hiroshi Kawaguchi、Nobuhiko Okui、Koichiro Sakaguchi、Eiji Okada
    • Journal Title

      Opto-electronics Review 16巻

      Pages: 404-412

    • Peer Reviewed
  • [Journal Article] 頭部組織の光伝播シミュレーションと脳機能計測2007

    • Author(s)
      川口拓之、岡田英史
    • Journal Title

      36巻

      Pages: 686-692

    • Peer Reviewed
  • [Presentation] 最先端光脳機能イメージング技術2009

    • Author(s)
      岡田英史
    • Organizer
      第30回日本レーザー医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-12-03
  • [Presentation] Evaluation of spatial resolution of near-infrared topography by a digital head phantom2009

    • Author(s)
      Eiji Okada
    • Organizer
      European Conference on Biomedical Optics
    • Place of Presentation
      Munich (Germany)
    • Year and Date
      2009-06-17
  • [Presentation] fNIRSの測定原理2008

    • Author(s)
      岡田英史
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-09
  • [Presentation] Evaluation of the image reconstruction algorithm for near infrared topography by virtual head phantom2007

    • Author(s)
      Eiji Okada
    • Organizer
      European Conference on Biomedical Optics
    • Place of Presentation
      Munich (Germany)
    • Year and Date
      2007-06-20
  • [Book] 精神疾患とNIRS光トポグラフィー検査による脳機能イメージング(NIRSデータのシミュレーション)2009

    • Author(s)
      川口拓之、岡田英史
    • Total Pages
      31-38
    • Publisher
      中山書店

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Published: 2011-06-18   Modified: 2016-04-21  

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