2009 Fiscal Year Final Research Report
Active dynamic manipulation and regenerative technique for damaged cells by using 3-D micro dynamic stimulation
| Project/Area Number |
19360106
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dynamics/Control
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| Research Institution | Yamagata University |
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Principal Investigator |
KOSAWADA Tadashi Yamagata University, 大学院・理工学研究科, 教授 (10143083)
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| Co-Investigator(Kenkyū-buntansha) |
FENG Zhonggang 山形大学, 大学院・理工学研究科, 准教授 (10332545)
GOTOU Kaoru 山形大学, 医学部, 教授 (30234975)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 細胞 / 動的力学刺激 / 3次元センサ・アクチュエータ / 培養ヒト骨芽細胞 / 蛍光観察 / ストレスファイバー制御 / 細胞活性化 |
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| Research Abstract |
A new micro actuator-sensor device was developed to induce mechanical local stimulation and to detect local mechanical cellular response. Then, an experimental system was established for cultured adhesive cells. The developed micro device has potentials as notonly a sensor to evaluate local mechanical property but also as an actuator to enforce mechanical local stimulation onto cultured living adhesive cells. The method has shown that the importance and effectiveness of the mechanical stimulations upon cellular activity particularly in the aspect of regenerative technique.
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Research Products
(25 results)
