2009 Fiscal Year Final Research Report
Analysis of mechanisms underlying maintenance of plant stem cells
Project/Area Number |
19370019
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
植物生理・分子
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Research Institution | Nara Institute of Science and Technology |
Principal Investigator |
UMEDA Masaaki Nara Institute of Science and Technology, バイオサイエンス研究科, 教授 (80221810)
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Co-Investigator(Kenkyū-buntansha) |
OKUSHIMA Yoko 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 (00432592)
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Project Period (FY) |
2007 – 2009
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Keywords | 幹細胞 / 細胞周期 / 分化全能性 / 細胞分裂 / 細胞分化 |
Research Abstract |
In this study, we focused on negative regulators of cell division to reveal molecular mechanisms underlying maintenance of plant stem cells. We found that some signal derived from very long chain fatty acid, which is produced in the epidermis of shoot apices, acts on inner cell layers to suppress stem cell division. Moreover, we developed a novel S phase-specific reporter gene by using the carboxy-terminal region of CDT1a to monitor cell proliferation in meristems.
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[Journal Article] SUMO E3 ligase HIGH PLOIDY2 regulates endocycle onset and meristem maintenance in Arabidopsis2009
Author(s)
Ishida, T., Fujiwara, S., Miura, K., Stacey, N., Yoshimura, M., Schneider, K., Adachi, S., Minamisawa, K., Umeda, M., Sugimoto, K.
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Journal Title
Plant Cell. 21
Pages: 2284-2297
Peer Reviewed
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[Journal Article] Targeted degradation of the cyclin-dependent kinase inhibitor ICK4/KRP6 by RING-type E3 ligases is essential for mitotic cell cycle progression during Arabidopsis gametogenesis2008
Author(s)
Liu, J., Zhang, Y., Qin, G., Tsuge, T., Sakaguchi, N., Luo, G., Sun, K., Shi, D., Aki, S., Zheng, N., Aoyama, T., Oka, A., Yang, W., Umeda, M., Xie, Q., Gu, H., Qu, L.-J.
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Journal Title
Plant Cell. 20
Pages: 1538-1554
Peer Reviewed
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[Journal Article] The rice FLATTENED SHOOT MERISTEM, encoding CAF-1 p150 subunit, is required for meristem maintenance by regulating the cell-cycle period2008
Author(s)
Abe, M., Kuroshita, H., Umeda, M., Itoh, J., Nagato Y.
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Journal Title
Dev. Biol. 319
Pages: 384-393
Peer Reviewed
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[Journal Article] The Arabidopsis D-type cyclin CYCD4 controls cell division in the stomatal lineage of the hypocotyl epidermis2007
Author(s)
Kono, A., Umeda-Hara, C., Adachi, S., Nagata, N., Konomi, M., Nakagawa, T., Uchimiya, H., Umeda, M.
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Journal Title
Plant Cell. 19
Pages: 1265-1277
Peer Reviewed
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[Journal Article] Potential roles for autophosphorylation, kinase activity, and abundance of a CDK-activating kinase (Ee;CDKF;1) during growth in leafy spurge2007
Author(s)
Chao, W.S., Serpe, M.D., Jia, Y., Shelver, W.L., Anderson, J.V., Umeda, M.
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Journal Title
Plant Mol. Biol. 63
Pages: 365-379
Peer Reviewed
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