2009 Fiscal Year Self-evaluation Report
Development of preventive therapy of no-se-induced hearing loss through clarifying its mechanism
| Project/Area Number |
19390168
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hygiene
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| Research Institution | Chubu University |
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Principal Investigator |
KATO Masashi Chubu University, 生命健康科学部, 教授 (10281073)
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| Project Period (FY) |
2007 – 2010
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| Keywords | シグナル伝達 / 環境ストレス / 労働衛生学 / 難聴 / 色素細胞 |
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| Research Abstract |
メラノサイト/メラニン制御分子にフォーカスを絞り、これらがどのようなメカニズムで内耳性難聴の発症や病態に影響を与えるのかをモデル動物を用いて分子レベルで解析する。さらに、騒音が、どのようなメカニズムでメラノサイト/メラニン制御分子の機能を修飾し、難聴を誘発するかを解明する。
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Research Products
(14 results)
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[Journal Article] NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo2009
Author(s)
Lakshmikanth T, Burke S, Ali TH, Kimpfler S, Ursini F, a Ruggeri L, Capanni M, Umansky V, Paschen A, Sucker A, Pende D, Groh V, Biassoni R, Hoglund P, Kato M, Shibuya K, Schadendorf D, Anichini A, Ferrone S, Velardi A, Karre K, Shibuya A, Carbone E, Colucci F.
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Journal Title
J Clin Invest 119(5)
Pages: 1251-63
Peer Reviewed
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[Journal Article] Ret-dependent cell rearrangements in the Wolffian duct pithelium initiate ureteric bud morphogenesis2009
Author(s)
Chi X, Michos O, Shakya R, Riccio P, Enomoto H, Licht JD, Asai N, Takahashi M, Ohgami N, Kato M, Mendelsohn C, Costantini F
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Journal Title
Dev Cell 17(2)
Pages: 199-209
Peer Reviewed
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