2009 Fiscal Year Final Research Report
The study on risk factors for prostate cancer according to production of equol, a metabolite of isoflavone.
| Project/Area Number |
19390176
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
MORI Mitsuru Sapporo Medical University, 医学部, 教授 (50175634)
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| Co-Investigator(Kenkyū-buntansha) |
TSUKAMOTO Taiji 札幌医科大学, 医学部, 教授 (50112454)
MASUMORI Naoya 札幌医科大学, 医学部, 准教授 (20295356)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 前立腺がん / 症例対照研究 / イソフラボン / エコール / 前立腺がんの家族歴 / 乳がんの家族歴 / 体重増加 / 交互作用 |
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| Research Abstract |
For equol producers with prostate cancer (PCa), family history of PCa, family history of breast cancer and weight gain≧10kg from 20 years old were significantly associated with elevated risk of PCa. Contrastly, for equol non-producer with PCa, family history of PCa was significantly associated with increased risk of PCa, but family history of breast cancer as well as weight gain≧10kg from 20 years old were not associated with risk of PCa. Accordingly, it has been suggested that a risk factor for PCa may be different between equol producer and equol non-producers.
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