2009 Fiscal Year Final Research Report

Quality evaluation of articular cartilage-delayed gadolinium-enhanced MRI and ultrasonic evaluation of cartilage

Research Project

Project/Area Number	19390391
Research Category	Grant-in-Aid for Scientific Research (B)
Allocation Type	Single-year Grants
Section	一般
Research Field	Orthopaedic surgery
Research Institution	Department of Clinical Research, National Hospital Organization Kyoto Medical Center (2008-2009) Kyoto University (2007)
Principal Investigator	NAKAGAWA Yasuaki Department of Clinical Research, National Hospital Organization Kyoto Medical Center, 臨床研究企画運営部, 研究員 (90293860)
Co-Investigator(Kenkyū-buntansha)	NAKAMURA Takashi 京都大学, 医学研究科, 教授 (10201675) KOBAYASHI Masahiko 京都大学, 医学研究科, 講師 (20378623)
Project Period (FY)	2007 – 2009
Keywords	軟骨 / 再生 / MRI / 超音波 / 評価
Research Abstract	The objective of this study was to evaluate the mechanical properties of the grafted cartilage, surrounding normal-like cartilage, the gap and the donor in second-look after mosaicplasty using our ultrasonic device and delayed gadolinium-enhanced MRI. At second-look, the grafted plugs had similar mechanical properties as normal after 1 year. Using delayed gadolinium-enhanced MRI, the quality of grafted plug cartilage restored 6 months after mosaicplasty in terms of GAG content.

(2 results)