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2009 Fiscal Year Final Research Report

Development of a prophylactic vaccine effective against a broader spectrum of HPVs associated with cervical cancer and basic research on therapeutic HPV vaccine for cervical cancer

Research Project

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Project/Area Number 19390424
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionUniversity of Tsukuba

Principal Investigator

YOSHIKAWA Hiroyuki  University of Tsukuba, 大学院・人間総合科学研究科, 教授 (40158415)

Co-Investigator(Kenkyū-buntansha) YASUGI Toshiharu  がん・感染症センター, 都立駒込病院婦人科, 医長 (20251267)
KAWANA Kei  東京大学, 医学部附属病院, 助教 (60311627)
Co-Investigator(Renkei-kenkyūsha) MATSUMOTO Kouji  筑波大学, 大学院・人間総合科学研究科, 講師 (30302714)
Project Period (FY) 2007 – 2009
KeywordsHPV / ワクチン / 子宮頸癌 / L2 / VLP
Research Abstract

The HPV 16/18 vaccine for prevention of cervical cancer is principally type-specific and can protect approximately 70% of cervical cancer. We developed a prophylactic vaccine effective against a broader spectrum of HPVs associated with cervical cancer. We now need clinical trial for clinical application.

  • Research Products

    (79 results)

All 2010 2009 2008 2007

All Journal Article (36 results) (of which Peer Reviewed: 27 results) Presentation (42 results) Book (1 results)

  • [Journal Article] Oral immunization with a Lactobacillus casei vaccine expressing human papillomavirus (HPV) type 16 E7 is an effective strategy to induce mucosal cytotoxic lymphocytes against HPV16 E72010

    • Author(s)
      Adachi K, Kawana K(13人中2番目), Yasugi T(13人中11番目), et al.
    • Journal Title

      Vaccine (in press)

    • Peer Reviewed
  • [Journal Article] Outcomes of Fertility-Sparing Surgery for Stage I Epithelial Ovarian Cancer : A Proposal for Patient Selection2010

    • Author(s)
      Satoh T, Yoshikawa H (20人中20番目)
    • Journal Title

      JCO 28(10)

      Pages: 1727-1732

    • Peer Reviewed
  • [Journal Article] The Optimal Debulking After Neoadjuvant Chemotherapy in Ovarian Cancer ; Proposal Based on Interval Look During Upfront Surgery Setting Treatment2010

    • Author(s)
      Onda T, Yoshikawa H (5人中2番目), Yasugi T (5人中3番目), et al.
    • Journal Title

      Jpn J Clin Oncol 40(1)

      Pages: 36-41

    • Peer Reviewed
  • [Journal Article] A Phase III Trial of Paclitaxel plus Carboplatin Versus Paclitaxel plus Cisplatin in Stage IVB, Persistent or Recurrent Cervical Cancer : Gynecologic Cancer Study Group/Japan Clinical Oncology Group Study (JCOG0505)2010

    • Author(s)
      Saito I, Yoshikawa H (8人中7番目), et al.
    • Journal Title

      Jpn J Clin Oncol 40(1)

      Pages: 90-93

    • Peer Reviewed
  • [Journal Article] Identification of nucleolin as a protein that binds to human papillomavirus type 16 DNA2009

    • Author(s)
      Sato H, Kawana K (11人中7番目), et al.
    • Journal Title

      Biochem Biophys Res Commun 387(3)

      Pages: 525-530

    • Peer Reviewed
  • [Journal Article] MR and CT findings of leiomyomatosis peritonealis disseminata with emphasis on assisted reproductive technology as a risk factor2009

    • Author(s)
      Tanaka YO, Yoshikawa H(9人中9番目), et al. Noguchi M, Minami M
    • Journal Title

      Br J Radiol 82(975)

      Pages: e44-47

    • Peer Reviewed
  • [Journal Article] Human papillomavirus infections among Japanese women : age-related prevalence and type-specific risk for cervical cancer2009

    • Author(s)
      Onuki M, Matsumoto K (12人中2番目), Yoshikawa H (12人中12番目), et al
    • Journal Title

      Cancer Sciences 100(7)

      Pages: 1312-1316

    • Peer Reviewed
  • [Journal Article] Human papillomavirus vaccines : current issues & future2009

    • Author(s)
      Kawana K (3人中1番目), Yasugi T (3人中2番目), et al.
    • Journal Title

      Indian J Med Res.Review 130(3)

      Pages: 341-347

    • Peer Reviewed
  • [Journal Article] Immunogenicity, reactogenicity and safety of human papillomavirus 16/18 AS04-adjuvanted vaccine in Japanese women : interim analysis of a phase II double-blind, randomized controlled trial at Month 72009

    • Author(s)
      Konno R, Yoshikawa H (5人中5番目), et al.
    • Journal Title

      Int J Gynecol Cancer 19(5)

      Pages: 905-911

    • Peer Reviewed
  • [Journal Article] Feasibility study of neoadjuvant chemotherapy followed by interval debulking surgery for stage III/IV ovarian, tubal, and peritoneal cancers : Japan Clinical Oncology Group Study JCOG02062009

    • Author(s)
      Onda T, Yoshikawa H (7人中7番目), et al.
    • Journal Title

      Gynecol Oncol 113(1)

      Pages: 57-62

    • Peer Reviewed
  • [Journal Article] Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment2009

    • Author(s)
      Abe K, Yoshikawa H (6人中5番目), et al.
    • Journal Title

      Experimental Hematology 37(4)

      Pages: 435-445.e1

    • Peer Reviewed
  • [Journal Article] Nuclear location of minor capsid protein L2 is required for expression of a reporter plasmid packaged in HPV51 pseudovirions2009

    • Author(s)
      Kondo K, Yoshikawa H (6人中5番目), et al.
    • Journal Title

      Virology 394(2)

      Pages: 259-265

    • Peer Reviewed
  • [Journal Article] A phase III randomized trial comparing neoadjuvant chemotherapy and upfront debulking surgery is indispensable as a basis for changing the standard treatment of advanced Mullerian cancer2009

    • Author(s)
      Onda T, Yoshikawa H (2人中2番目)
    • Journal Title

      Gynecol Oncol 114(2)

      Pages: 371-372

    • Peer Reviewed
  • [Journal Article] ヒトパピローマウイルス2009

    • Author(s)
      吉川裕之
    • Journal Title

      がん分子標的治療(メディカルレビュー社、東京) 7(2)

      Pages: 54-57

  • [Journal Article] ヒトパピローマウイルス2009

    • Author(s)
      吉川裕之
    • Journal Title

      日本医師会雑誌(日本医師会 (東京)) 138(4)

      Pages: 697-699

  • [Journal Article] ヒトパピローマウイルス (HPV) ワクチン2009

    • Author(s)
      吉川裕之
    • Journal Title

      化学療法の領域(医学ジャーナル社(東京)) 25(7)

      Pages: 65-70

  • [Journal Article] 日本におけるHPVワクチンの接種-現状と展望-2009

    • Author(s)
      吉川裕之
    • Journal Title

      産婦人科治療(永井書店) 99(3)

      Pages: 311-315

  • [Journal Article] HPVワクチンによる癌予防2009

    • Author(s)
      吉川裕之
    • Journal Title

      感染制御(EDIXi出版部(東京)) 5(4)

      Pages: 343-346

  • [Journal Article] 「ワクチンへの期待」子どもの健康科学2009

    • Author(s)
      吉川裕之
    • Journal Title

      日本子ども健康科学学会 10(1)

      Pages: 23-27

  • [Journal Article] Japan Clinical Oncology Group. Phase III trial of upfront debulking surgery versus neoadjuvant chemotherapy for stage III/IV ovarian, tubal and peritoneal cancers : Japan Clinical Oncology Group Study JCOG06022008

    • Author(s)
      Onda T, Yoshikawa H (8人中8番目)
    • Journal Title

      Jpn J Clin Oncol 38(1)

      Pages: 74-77

    • Peer Reviewed
  • [Journal Article] Carcinosarcoma of the uterus : MR findings2008

    • Author(s)
      Tanaka YO, Yoshikawa H (5人中4番目), et al.
    • Journal Title

      J Magn Reson Imaging 28(2)

      Pages: 434-439

    • Peer Reviewed
  • [Journal Article] Comparison of tumor regression rate of uterine cervical squamous cell carcinoma during external beam and intracavitary radiotherapy2008

    • Author(s)
      Ohara K, Yoshikawa H (7人中7番目), et al.
    • Journal Title

      Radiat Med 26(9)

      Pages: 526-532

    • Peer Reviewed
  • [Journal Article] Silent venous thromboembolism before treatment in endometrial cancer and the risk factors2008

    • Author(s)
      Satoh T, Matsumoto K (11人中2番目), Yoshikawa H (11人中11番目), et al.
    • Journal Title

      Br J Cancer 99(7)

      Pages: 1034-1039

    • Peer Reviewed
  • [Journal Article] Neutralizing antibodies against human papillomavirus types of 16, 18, 31, 52, and 58 in the serum samples from Japanese women with low grade cervical intraepithelial neoplasia2008

    • Author(s)
      Ochi H, Matsumoto K (9人中3番目), Yasugi T (9人中5番目), Yoshikawa H (9人中8番目), et al.
    • Journal Title

      Clin Vaccine Immunol 15(10)

      Pages: 1536-1540

    • Peer Reviewed
  • [Journal Article] Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes2008

    • Author(s)
      Kondo K, Yoshikawa H (5人中4番目), et al.
    • Journal Title

      J Med Virol 80(5)

      Pages: 841-846

    • Peer Reviewed
  • [Journal Article] 「性感染症の最前線HPV感染と子宮頸癌-これまでの研究の流れ-」臨床とウイルス2008

    • Author(s)
      吉川裕之
    • Journal Title

      日本臨床ウイルス学会 36(5)

      Pages: 377-383

  • [Journal Article] Outcomes of Fertility-Sparing Surgery for Stage I Epithelial Ovarian Cancer : A Proposal for Patient Selection. JCO, in pressnation for the failure of neoadjuvant chemotherapy to improve outcomes after radiotherapy for locally advanced uterine cervical cancer from the standpoint of the tumor regression rate2007

    • Author(s)
      Ohara K, Yoshikawa H (12人中11番目), et al. ExplaSatoh T, Yoshikawa H (20人中20番目)
    • Journal Title

      Radiat Med 25

      Pages: 53-59

    • Peer Reviewed
  • [Journal Article] Magnetic resonance findings of primary uterine malignant lymphoma2007

    • Author(s)
      Goto N, Yoshikawa H (5人中4番目), et al.
    • Journal Title

      Magn Reson Med Sci 6(1)

      Pages: 7-13

    • Peer Reviewed
  • [Journal Article] Combined phospho-Akt and PTEN expressions associated with post-treatment hysterectomy after conservative progestin therapy in complex atypical hyperplasia and stage Ia, G1 adenocarcinoma of the endometrium2007

    • Author(s)
      Minaguchi T, Yasugi T (12人中8番目), Yoshikawa H (12人中11番目), et al.
    • Journal Title

      Cancer Letters 248(1)

      Pages: 112-122

    • Peer Reviewed
  • [Journal Article] Neutralization of HPV16, 18, 31, and 58 pseudovirions with antisera induced by immunizing rabbits with synthetic peptides representing segments of the HPV16 minor capsid protein L2 surface region2007

    • Author(s)
      Kondo K, Yoshikawa H, (6人中5番目)
    • Journal Title

      Virology 358(2)

      Pages: 266-272

    • Peer Reviewed
  • [Journal Article] Treatment with paclitaxel plus carboplatin, alone or with irradiation, of advanced or recurrent endometrial carcinoma2007

    • Author(s)
      Arimoto T, Yasugi T (7人中3番目), Yoshikawa H (7人中4番目), Kawana K (7人中5番目), et al.
    • Journal Title

      Gynecol Oncol 104(1)

      Pages: 32-35

    • Peer Reviewed
  • [Journal Article] Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer2007

    • Author(s)
      Uno K, Matsumoto K (12人中6番目), Yoshikawa H (12人中11番目), et al.
    • Journal Title

      Br J Cancer 96(2)

      Pages: 290-295

    • Peer Reviewed
  • [Journal Article] Fertility-Sparing Treatment with Medroxyprogesterone Acetate for Endometrial Carcinoma and Atypical Hyperplasia in Young Women : A Multicenter Phase II Study2007

    • Author(s)
      Ushijima K, Yoshikawa H (20人中3番目), Yasugi T (20人中5番目), et al.
    • Journal Title

      J Clin Oncol 25(19)

      Pages: 2798-2803

    • Peer Reviewed
  • [Journal Article] High incidence of silent venous thromboembolism before treatment in ovarian cancer2007

    • Author(s)
      Satoh T, Matsumoto K (12人中8番目), Yoshikawa H (12人中12番目), et al.
    • Journal Title

      Br J Cancer 97(8)

      Pages: 1053-1057

    • Peer Reviewed
  • [Journal Article] ワクチンの展望1ヒトパピローマウイルス (HPV) ワクチン2007

    • Author(s)
      吉川裕之
    • Journal Title

      治療学(ライフサイエンス出版株式会社) 41(10)

      Pages: 55-57

  • [Journal Article] HPVワクチンと子宮頸癌の予防2007

    • Author(s)
      吉川裕之
    • Journal Title

      産婦人科治療(永井書店) 95(3)

      Pages: 299-302

  • [Presentation] 子宮頸癌予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      京都HPVワクチン学術講演会
    • Place of Presentation
      京都
    • Year and Date
      2010-03-27
  • [Presentation] ワクチンによる子宮頸癌予防戦略2010

    • Author(s)
      吉川裕之
    • Organizer
      第8回神奈川県県域地区産婦人科研修会
    • Place of Presentation
      神奈川
    • Year and Date
      2010-03-11
  • [Presentation] 子宮頸がんの予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Place of Presentation
      鹿児島
    • Year and Date
      2010-02-24
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2010

    • Author(s)
      吉川裕之
    • Organizer
      平成21年度大分県医師会がん精密検診協力医療機関研修会 大分県医師会
    • Place of Presentation
      大分
    • Year and Date
      2010-01-31
  • [Presentation] 講演「子宮頸がん予防ワクチンについて」2010

    • Author(s)
      吉川裕之
    • Organizer
      鳥取産婦人科医会・西部小児科医会合同特別講演会
    • Place of Presentation
      鳥取
    • Year and Date
      2010-01-21
  • [Presentation] ワクチンによる子宮頸がん予防戦略2010

    • Author(s)
      吉川裕之
    • Organizer
      がん医療水準的てん化研修会「バーチャルスライド、ベセスダシステム、HPVに関する研修会」
    • Place of Presentation
      札幌
    • Year and Date
      2010-01-09
  • [Presentation] ワクチンによる子宮頸癌の予防2009

    • Author(s)
      吉川裕之
    • Organizer
      第24回北海道抗ウイルス療法研究会
    • Place of Presentation
      札幌
    • Year and Date
      20090616-20090617
  • [Presentation] CIN患者におけるHPV血清中和抗体2009

    • Author(s)
      越智寛幸, 松本光司, 吉川裕之, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Year and Date
      20090403-20090405
  • [Presentation] 次世代型HPVワクチンの開発2009

    • Author(s)
      近藤一成, 吉川裕之, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Year and Date
      20090403-20090405
  • [Presentation] 我が国におけるHPV感染とタイプ別子宮頸癌リスク-スクリーニングとワクチンのための基礎データ-2009

    • Author(s)
      小貫麻美子, 松本光司, 他
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Year and Date
      20090403-20090405
  • [Presentation] HPVワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Year and Date
      20090403-20090405
  • [Presentation] 子宮頸癌予防ワクチン (HPV-16/18AS04) の本邦における中間解析と臨床的意義2009

    • Author(s)
      今野良, 吉川裕之
    • Organizer
      第61回日本産科婦人科学会学術講演会
    • Place of Presentation
      京都
    • Year and Date
      20090403-20090405
  • [Presentation] 子宮頸癌予防のためのHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      長野市医師会学術講演会
    • Place of Presentation
      長野
    • Year and Date
      2009-12-17
  • [Presentation] HPVワクチンによる子宮頸癌予防2009

    • Author(s)
      吉川裕之
    • Organizer
      平成21年度第3回滋賀県産婦人科医会
    • Place of Presentation
      滋賀県 (大津)
    • Year and Date
      2009-12-06
  • [Presentation] 子宮頸がん予防とHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      婦人科臨床懇話会HPV研究会 愛知県産婦人科医会
    • Place of Presentation
      愛知
    • Year and Date
      2009-11-28
  • [Presentation] 子宮頸癌予防戦略としてのワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      第1回県南県西子宮頸癌予防セミナー
    • Place of Presentation
      つくば
    • Year and Date
      2009-11-26
  • [Presentation] ワクチンによる子宮頸癌予防戦略2009

    • Author(s)
      吉川裕之
    • Organizer
      第282回筑後ブロック産婦人科医会研修会
    • Place of Presentation
      久留米
    • Year and Date
      2009-11-18
  • [Presentation] HPVワクチンの効果と安全性2009

    • Author(s)
      吉川裕之
    • Organizer
      子宮頸がん予防のためのプロフェッショナルワークショップ
    • Place of Presentation
      東京
    • Year and Date
      2009-11-15
  • [Presentation] 特別講演「子宮頸がんの予防ワクチンについて」2009

    • Author(s)
      吉川裕之
    • Organizer
      山梨ウイルス研究会
    • Place of Presentation
      山梨
    • Year and Date
      2009-10-30
  • [Presentation] HPVワクチンによる子宮頸癌予防2009

    • Author(s)
      吉川裕之
    • Organizer
      第235回広島市臨床産婦人科医会研修会
    • Place of Presentation
      広島
    • Year and Date
      2009-09-24
  • [Presentation] ワクチンによる子宮頸がんの予防2009

    • Author(s)
      吉川裕之
    • Organizer
      北陸ウイルス研究会
    • Place of Presentation
      金沢
    • Year and Date
      2009-09-05
  • [Presentation] 子宮頸がん予防のためのHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      第10回臨床腫瘍夏期セミナー
    • Place of Presentation
      東京
    • Year and Date
      2009-07-23
  • [Presentation] 子宮頸癌ワクチンの展望(日医生涯教育協力講座 セミナー「ウイルス感染症をめぐる最新の動向」)2009

    • Author(s)
      吉川裕之
    • Organizer
      茨城県医師会会館
    • Place of Presentation
      水戸
    • Year and Date
      2009-04-11
  • [Presentation] 「子宮頸がんの現状とワクチン」子宮がんセミナー2009

    • Author(s)
      吉川裕之
    • Organizer
      公明党女性委員会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-28
  • [Presentation] HPVワクチン開発と導入、その課題-HPV感染と子宮頸癌、ワクチンによる予防の課題-2009

    • Author(s)
      吉川裕之
    • Organizer
      第一回HPVワクチン推奨ワーキンググループ 日本産婦人科医会
    • Place of Presentation
      東京
    • Year and Date
      2009-02-20
  • [Presentation] 子宮頸がんの現状とHPVワクチン2009

    • Author(s)
      吉川裕之
    • Organizer
      世界対がんデー公開シンポジウム-子宮頸がん征圧を目指して-
    • Place of Presentation
      東京 (癌研)
    • Year and Date
      2009-02-04
  • [Presentation] 子宮頸がんワクチンの現状と展望について2009

    • Author(s)
      吉川裕之
    • Organizer
      第24回奈良感染症研究会
    • Place of Presentation
      奈良
    • Year and Date
      2009-01-24
  • [Presentation] 子宮頸癌ワクチンの展望2009

    • Author(s)
      吉川裕之
    • Organizer
      日医生涯教育協力講座 (セミナー・ウイルス感染症における予防と治療)
    • Place of Presentation
      高知
    • Year and Date
      2009-01-17
  • [Presentation] 子宮頸癌とHPV-頸癌の Pathogenesis とHPVの疫学2008

    • Author(s)
      吉川裕之
    • Organizer
      第116回日本産科婦人科学会関東連合地方部会
    • Place of Presentation
      栃木
    • Year and Date
      20081129-20081130
  • [Presentation] The Standard Treatment of Cervical Cancer in Asian View-Point2008

    • Author(s)
      Yoshikawa H
    • Organizer
      The 3rd Biennial Conference Asia Oceania research organization on Genital Infection & Neoplasia (AOGIN 2008)
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      20080529-20080531
  • [Presentation] 子宮頸部HPV感染症の疫学研究とワクチンによる予防2008

    • Author(s)
      吉川裕之
    • Organizer
      第82回日本感染症学会総会・学術講演会
    • Place of Presentation
      島根
    • Year and Date
      20080417-20080418
  • [Presentation] ワクチンへ期待2008

    • Author(s)
      吉川裕之
    • Organizer
      第10回こども健康科学学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-12-06
  • [Presentation] ワクチンによる子宮頸がんの予防2008

    • Author(s)
      吉川裕之
    • Organizer
      長崎県産婦人科学術講演会
    • Place of Presentation
      長崎
    • Year and Date
      2008-11-07
  • [Presentation] HPVワクチンによる子宮頸がんの予防2008

    • Author(s)
      吉川裕之
    • Organizer
      第11回熊本ウイルス感染症研究会
    • Place of Presentation
      熊本
    • Year and Date
      2008-10-16
  • [Presentation] 電流検出型DNAチップ法によるHPVタイピング試薬の臨床的有用性2008

    • Author(s)
      佐藤豊実, 吉川裕之, 他
    • Organizer
      第40回日本臨床検査自動科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-10
  • [Presentation] HPVと関連疾患2008

    • Author(s)
      吉川裕之
    • Organizer
      HPV Vaccine International Meeting
    • Place of Presentation
      東京
    • Year and Date
      2008-09-19
  • [Presentation] Development of novel HPV genotyping chip system using electrochemical detection technology and Non-PCR amplification technology2007

    • Author(s)
      Satoh T, Matsumoto K, Yoshikawa H, et al.
    • Organizer
      24th international papillomavirus conference and clinical workshop
    • Place of Presentation
      Beijing, China
    • Year and Date
      20071103-20071109
  • [Presentation] 子宮癌の予防に向けて2007

    • Author(s)
      吉川裕之
    • Organizer
      第48回日本母性衛生学会総会・学術集会
    • Place of Presentation
      つくば
    • Year and Date
      20071011-20071012
  • [Presentation] HPV感染による子宮頸癌への対応2007

    • Author(s)
      吉川裕之
    • Organizer
      第22回関東甲信静支部ウィルス研究部会総会
    • Place of Presentation
      茨城
    • Year and Date
      20070927-20070928
  • [Presentation] Development of novel HPV genotyping chip system using electrochemical detetion technology2007

    • Author(s)
      Satoh T, Matsumoto K, Yoshikawa H, et al.
    • Organizer
      2007 AACC Annal Meeting
    • Place of Presentation
      California. USA
    • Year and Date
      20070715-20070719
  • [Presentation] 子宮頸がんワクチンの現状と展望2007

    • Author(s)
      吉川裕之
    • Organizer
      第25回日本産婦人科学感染症研究会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2007-06-16
  • [Presentation] 子宮頸がんの現状と予防への期待2007

    • Author(s)
      吉川裕之
    • Organizer
      Dr.Ian Frazer 来日メディアセミナー
    • Place of Presentation
      東京
    • Year and Date
      2007-06-12
  • [Book] Human papillomavirus type 16 capsid proteins : Immunogenecity and possible use as prophylactic vaccine antigens(Ed. Cheng R. H., Miyamura T.)Structure-based study of viral replication2008

    • Author(s)
      Kanda T, Kawana K, Yoshikawa H
    • Total Pages
      539-552
    • Publisher
      World Scientific Publishing

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

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