2009 Fiscal Year Final Research Report
Molecular approaches to identify molecules involved in the cell aggregates formation in the skeletal blastema and elucidation of their functional properties
| Project/Area Number |
19390475
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Functional basic dentistry
|
|---|
| Research Institution | Tsurumi University |
|---|
Principal Investigator |
NIFUJI Akira Tsurumi University, 歯学部, 教授 (00240747)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SHIBATA Tatsuya 鶴見大学, 歯学部, 助教 (90323708)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
ARAKI Ryoko 放射線医学総合研究所, 重粒子医科学センター, チームリーダー (40392211)
|
|---|
| Project Period (FY) |
2007 – 2009
|
| Keywords | 薬理学 / 分化 / 遺伝子 / 発生 / 骨格形成 |
|---|
| Research Abstract |
During skeletal development, the skeletal blastema starts from cell aggregates formation in the mesoderm tissue. To understand skeletal tissue formation, it is crucial to elucidate molecular mechanism how cell aggregates are formed. In this study we aimed to establish molecular approaches to identify functional molecules involved in the cell aggregates formation and to analyze their expressions and functions. Through these approaches, we identified and characterized several molecules that may function in the skeletal blastema.
|
Research Products
(23 results)
-
-
-
-
-
-
[Journal Article] Ihh/Gli2 Signaling Promotes Osteoblast Differentiation by Regulating Runx2 Expression and Function2007
Author(s)
Shimoyama A, Wada M, Ikeda F, Hata K, Matsubara T, Nifuji A, Noda M, Amano K, Yamaguchi A, Nishimura R, Yoneda T
-
Journal Title
Mol Biol Cell 18(7)
Pages: 2411-8
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
