2009 Fiscal Year Final Research Report
Genetic epidemiological research on drug resistant malaria which has originated and been spreading in Asian countries.
| Project/Area Number |
19406013
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Parasitology (including Sanitary zoology)
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| Research Institution | Research Institute, International Medical Center of Japan |
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Principal Investigator |
KANO Shigeyuki Research Institute, International Medical Center of Japan, 研究所, 部長 (60233912)
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| Co-Investigator(Kenkyū-buntansha) |
MITAMURA Toshihide 国立国際医療センター, 研究所, 室長 (61099925)
HATABU Toshimitsu 群馬大学, 医学部, 助教 (60344917)
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| Co-Investigator(Renkei-kenkyūsha) |
IWAGAMI Moritoshi 国立国際医療センター, 研究所, 研究員 (20392392)
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| Research Collaborator |
TANABE Kazuyuki 大阪大学, 微生物病研究所, 教授
KAWAZU Shin-Ichiro 帯広畜産大学, 原虫病センター, 教授
NAKAZAWA Shusuke 長崎大学, 熱帯医学研究所, 助教
TONGOL-RIVERA Pilarita フィリピン大学, 公衆衛生学部, 教授
LOOAREESUWAN Sornchai フィリピン大学, 公衆衛生学部, 教授
LOOAREESUWAN Sornchai タイ・マヒドン大学, 熱帯医学部, 教授
KRUDSOOD Srivicha タイ・マヒドン大学, 熱帯医学部, 教授
KHO Weon-Gyu 韓国・インジェ大学, 医学部, 教授
SOCHEAT Duong ラオス保健省・寄生虫学・昆虫学・マラリア対策センター, 所長
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| Project Period (FY) |
2007 – 2009
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| Keywords | 遺伝学 / 感染症 / ゲノム / 疫学 / マラリア |
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| Research Abstract |
In the malaria endemic Philippines, the level of genetic diversity of Plasmodium falciparum correlates with the local malaria endemicity. The Thai P.f.populations had been under strong chloroquine selective pressure but the Vietnamese population had not, and that the origin of chloroquine resistance in Vietnam might be different from Thailand. The genealogical origin of P. vivax populations in South Korea was from the two different populations in southern China. These findings confirm that population genetic analyses are a useful tool for epidemiology of malaria.
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Research Products
(30 results)
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[Presentation] ンの熱帯熱マラリア原虫集団の遺伝的構造と流行度2008
Author(s)
石上盛敏, リベラピラリタ, ヴィラコルテエレーナ, エスクエタアレイラ, 畑生俊光, 河津信一郎, 早川敏之, 田邉和裄, 狩野繁之
Organizer
第49回日本熱帯医学会大会・第23回日本国際保健医療学会学術大会合同大会
Place of Presentation
国立国際医療センター
Year and Date
20081025-20081026
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[Presentation] Analyses of microsatellite polymorphisms flanking the the pfcrt gene of Plasmodium falciparum showed different modes of evolution of chloroquine resistance in Thailand and Vietnam.2008
Author(s)
Iwagami M, Susomboon P, Tangpukdee N, Wilairatana P, Krudsood S, Dao LD, Tuan NV, Phuc BQ, Giang ND, Nakazawa S, Looareesuwan S, Kano S
Organizer
Joint International Tropical Medicine Meeting 2008
Place of Presentation
Imperial Queen's Park Hotel, Bangkok
Year and Date
20081013-20081014
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