2009 Fiscal Year Final Research Report
Transitions between "internal states" in the brain viewed as quasi-attractors- A mathematical and neurodynamical approach
| Project/Area Number |
19500259
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | Kyoto Sangyo University |
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Principal Investigator |
FUJII Hiroshi Kyoto Sangyo University, コンピュータ理工学部, 教授 (90065839)
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| Co-Investigator(Kenkyū-buntansha) |
TSUDA Ichiro 北海道大学, 電子科学研究所, 教授 (10207384)
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| Project Period (FY) |
2007 – 2009
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| Keywords | トップダウン注意 / 疑アトラクタ / 皮質の状態遷移 / GABA放出の前シナプス抑制 / ムスカリン様アセチルコリン受容体 / 皮質求心性アセチルコリン / マイネルト核 / レビ小体型認知症と幻覚 |
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| Research Abstract |
We presented a scenario on the possible mechanism of cortical state transitions which occur associated with the arrival of top-down attention (s). This study would provide the basic framework for mathematical study and modeling of such cortical state transitions. We argue how the three physiological mechanisms including the corticopetal acetylcholine induce transient reconstruction of attractors, which simultaneously work in the layer 1 and 2/3 with top-down attentional glutamatergic spike volleys.
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