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2009 Fiscal Year Final Research Report

Noninvasive acquisition of ischemic tolerance of brain after spreading depression by transcranial magnetic stimulation

Research Project

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Project/Area Number 19500312
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Nerve anatomy/Neuropathology
Research InstitutionKeio University

Principal Investigator

KOBAYASHI Masahito  Keio University, 医学部, 講師 (60245511)

Co-Investigator(Kenkyū-buntansha) HORIGUCHI Takashi  慶應義塾大学, 医学部, 講師 (70245520)
Project Period (FY) 2007 – 2009
Keywords脳虚血耐性 / 経頭蓋磁気刺激 / 皮質拡散抑制
Research Abstract

We have established the condition of general anesthesia and chemical stimulation to induce SD in the experimental animal connected to the stereotactic neurosurgical frame. While TMS itself was difficult to induce SD constantly, high-frequency repetitive TMS reduced threshold to induce the SD by chemical stimulation.

  • Research Products

    (9 results)

All 2010 2009 2008 2007

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (6 results)

  • [Journal Article] Effect of slow repetitive TMS of the motor cortex on ipsilateral sequential simple finger movements and motor skill learning2010

    • Author(s)
      Masahito Kobayashi
    • Journal Title

      Restorative Neurology and Neuroscience (印刷中)

    • Peer Reviewed
  • [Journal Article] Suppression of ipsilateral motor cortex facilitates motor skill learning2009

    • Author(s)
      Masahito Kobayashi
    • Journal Title

      European Journal of Neuroscience 29巻

      Pages: 833-836

    • Peer Reviewed
  • [Journal Article] Source analysis of the magnetic field evoked during self-paced finger movements2008

    • Author(s)
      Maki Niimi、Masahito Kobayashi
    • Journal Title

      Neurological Research 30巻

      Pages: 239-243

    • Peer Reviewed
  • [Presentation] 経頭蓋磁気刺激による脳卒中および頭頚部外傷後慢性期の難治性疼痛の制御2009

    • Author(s)
      小林正人
    • Organizer
      第48回日本定位・機能神経外科学会
    • Place of Presentation
      東京
    • Year and Date
      2009-01-23
  • [Presentation] 経頭蓋磁気刺激による脳脊髄損傷後慢性期の治療の試み2008

    • Author(s)
      小林正人
    • Organizer
      第38回日本臨床神経生理学会学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-11-13
  • [Presentation] Characteristics of neuronal activation in the primary sensori-motor cortex under chronic ischemia and its change through surgical intervention2008

    • Author(s)
      秋山武紀、小林正人
    • Organizer
      Conference of International Society for the Advancement of Clinical Magnetoencephalography
    • Place of Presentation
      Matsushima, Japan
    • Year and Date
      2008-08-30
  • [Presentation] Somatosensory evoked field derived by tactile finger stimulation2008

    • Author(s)
      井麻綾、小林正人
    • Organizer
      Conference of International Society for the Advancement of Clinical Magnetoencephalography
    • Place of Presentation
      Matsushima, Japan
    • Year and Date
      2008-08-30
  • [Presentation] 経頭蓋磁気刺激による頭頸部外傷後の慢性期の疼痛の制御2008

    • Author(s)
      小林正人
    • Organizer
      日本定位・機能的脳神経外科学会
    • Place of Presentation
      浜松
    • Year and Date
      2008-01-26
  • [Presentation] 3T-MRIを用いた定位脳手術planningの誤差と有用性の検討2007

    • Author(s)
      小林正人
    • Organizer
      第25回関東機能的脳外科カンファレンス
    • Place of Presentation
      東京
    • Year and Date
      2007-09-01

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Published: 2011-06-18   Modified: 2016-04-21  

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