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2009 Fiscal Year Final Research Report

Correlation between olfactory stimulation and transduction cascade within the sensory cilia

Research Project

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Project/Area Number 19500350
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Neurophysiology and muscle physiology
Research InstitutionOsaka University

Principal Investigator

KURAHASHI Takashi  Osaka University, 大学院・生命機能研究科, 教授 (90225251)

Project Period (FY) 2007 – 2009
KeywordsCa / cAMP / 嗅覚 / ケージド化合物 / 繊毛
Research Abstract

Olfaction starts at the olfactory sensory cilia which have nano-scale structure. In the olfactory transduction cascade, it is an important because Ca can cause olfactory adaptation and non-linear signal amplification. In this project, we solve the problem that had been left conventionally by monitoring the molecular dynamics.

  • Research Products

    (9 results)

All 2009

All Journal Article (1 results) Presentation (8 results)

  • [Journal Article] Mechanism of olfactory masking in the sensory cilia.2009

    • Author(s)
      Takeuchi H, Ishida H, Hikichi S, Kurahashi T.
    • Journal Title

      Journal of General Physiology. 133

      Pages: 583-60

  • [Presentation] 嗅繊毛内におけるセカンドメッセンジャーの散制限:電流解析と可視化.2009

    • Author(s)
      竹内裕子、倉橋隆
    • Organizer
      近畿生理学談話会
    • Place of Presentation
      大阪大学
    • Year and Date
      2009-12-13
  • [Presentation] 塩酸コカインによる嗅細胞Na+電流の抑制作用と安全性検討.2009

    • Author(s)
      玉利健悟、竹内裕子、小林正佳、倉橋隆、山本哲朗
    • Organizer
      近畿生理学談話会
    • Place of Presentation
      大阪大学
    • Year and Date
      2009-12-13
  • [Presentation] 嗅覚マスキングと匂い物質による電位依存性Kチャネルの抑制.2009

    • Author(s)
      吉田太一、竹内裕子、倉橋隆
    • Organizer
      近畿生理学談話会
    • Place of Presentation
      大阪大学
    • Year and Date
      2009-12-13
  • [Presentation] Nano-Manipulation of Olfactory Sensation.2009

    • Author(s)
      Hiroko Takeuchi, Takashi Kurahashi, Hirohiko Ishida, Satoshi Hikichi.
    • Organizer
      IUPS(国際生理科学連合)大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-08-01
  • [Presentation] Visualization and quantitative analysis of the nano-scale olfactory sensory cilia.2009

    • Author(s)
      Yukako Kishino, Hiroko Takeuchi, Takashi Kurahashi.
    • Organizer
      IUPS(国際生理科学連合)大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-08-01
  • [Presentation] Mechanism of olfactory masking in the sensory cilia.2009

    • Author(s)
      Hiroko Takeuchi, Takashi Kurahashi
    • Organizer
      IUPS(国際生理科学連合)大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-07-30
  • [Presentation] Suppression by odorants of newt olfactory voltage-gated ion channels of receptor cells.2009

    • Author(s)
      Taichi Yoshida, Hiroko Takeuchi, Takashi Kurahashi
    • Organizer
      IUPS(国際生理科学連合)大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-07-30
  • [Presentation] Single K channels in the newt olfactory receptor neuron.2009

    • Author(s)
      Ryo Sakane, Takashi Kurahashi
    • Organizer
      IUPS(国際生理科学連合)大会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2009-07-29

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Published: 2011-06-18   Modified: 2016-04-21  

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