• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2008 Fiscal Year Final Research Report

Development of the therapeutic and diagnostic technology for vascular lesion using a complex of gold-nanospheres and indocyanine green

Research Project

  • PDF
Project/Area Number 19500395
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Biomedical engineering/Biological material science
Research InstitutionJuntendo University

Principal Investigator

MORIMOTO Yuji  Juntendo University, 医学部, 講師 (10449069)

Co-Investigator(Kenkyū-buntansha) NAKAI Kanji  順天堂大学, 医学部, 講師 (20420838)
Project Period (FY) 2007 – 2008
Keywords金ナノ粒子 / インドシアニングリーン / ポリエチレングリコール / 吸光 / 蛍光 / プラスモン共鳴
Research Abstract

電磁波エネルギーに反応する多機能ナノデバイスとして、生体安全性の確立されている色素、インドシアニングリーン(ICG)と金ナノ粒子(GNP, ~60nm)の結合体(ICG-GNP)を創製し、基本特性を評価した。その結果、ICG-GNPは細胞内に取り込まれ、近赤外光によって励起される蛍光標識の役割を果たすことを確認した。本結果より、ICG-GNPは動脈硬化診断・治療に適用できることが示唆された。

  • Research Products

    (5 results)

All 2008 2007

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Detection of skin perforators by indocyanine green fluorescence near infrared angiography2008

    • Author(s)
      Y. Morimoto, (他8名)
    • Journal Title

      Plastic and Reconstructive Surgery 122

      Pages: 1062-1067

    • Peer Reviewed
  • [Journal Article] Novel lymphography using indocyanine green dye for near-infrared fluorescence labeling2007

    • Author(s)
      Y. Morimoto, (他4名)
    • Journal Title

      Annals of Plastic Surgery 58

      Pages: 652-655

    • Peer Reviewed
  • [Presentation] 高コレステロール餌ウサギモデルにおける動脈硬化の検討2007

    • Author(s)
      Y. Morimoto, (他6名)
    • Organizer
      第39回日本動脈硬化学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-14
  • [Presentation] Real time molecular imaging using gold nanoparticles and a dark-field microscope2007

    • Author(s)
      Y. Morimoto, (他5名)
    • Organizer
      98th Annual Meeting 2007-American Association for Cancer Research
    • Place of Presentation
      米国
    • Year and Date
      2007-04-18
  • [Presentation] Novel lymphography using indocyanine green dye for near-infrared fluorescence labeling2007

    • Author(s)
      Y. Morimoto, (他5名)
    • Organizer
      98th Annual Meeting 2007-American Association for Cancer Research
    • Place of Presentation
      米国
    • Year and Date
      2007-04-18

URL: 

Published: 2010-06-10   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi