2009 Fiscal Year Final Research Report
Cell function on nano-surface of hydroxyapatite nanocrystal composite
| Project/Area Number |
19500411
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
FURUZONO Tsutomu National Cardiovascular Center Research Institute, 生体工学部, 室長 (30332406)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 生体機能材料 |
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| Research Abstract |
Cell functions of cells on hydroxyapatite (HAp) nanoparticles coated on polyethyleneterephtalete (PET) sheet were examined in detail. Cell adhesiveness and proliferation on HAp sheet was higher than original PET sheet. It was thought that the higher adhesion strength of cells on HAp substrate compare to the on original PET depend on cell anchoring on nano-structure and higher remodeling of extracellular matrix.
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