2009 Fiscal Year Final Research Report
Search for saliva biomarkers used for mental health management of junior high school student
| Project/Area Number |
19500473
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Iwate University (2008-2009)
University of Toyama (2007) |
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Principal Investigator |
YAMAGUCHI Masaki Iwate University, 工学部, 教授 (50272638)
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| Co-Investigator(Kenkyū-buntansha) |
TAKEDA Kazunori 筑波大学, 大学院・人間総合科学研究科, 教授 (90261768)
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| Project Period (FY) |
2007 – 2009
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| Keywords | バイオマーカー / モニタリング / 唾液 / 児童生徒 / ストレス / 情動 / 交感神経 / センサ |
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| Research Abstract |
In order to search for salivary biomarkers used for the mental health management of junior high school student, a psychosomatic stress test, a search for salivary biomarkers and an improvement on the psychology education were carried out. It was revealed that the salivary amylase activity (sAA) statistically correlate with the subjective evaluation of psychosomatic stress from a salivary test using seventy healthy subjects in first-year junior high school students for 3 weeks. Three salivary stress markers, sAA as an index of sympathetic nervous system, salivary cortisol (sCORT) as an index of endocrine system and salivary IgA (sIgA) as an index of immune system, were identified through the psychosomatic stress test. It was indicated that the salivary stress markers might be a useful screening method for preventing to be a non-attendance at school using the multiple regression analysis.
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[Patent(Industrial Property Rights)] アミラーゼ活性測定キット2009
Inventor(s)
山口 昌樹, 吉田 博, 渥美 尚大, 木村 定明, 鈴木 一人, 東 朋幸, 松田 篤志, 草場 宣廷, 水野 康文, 橋本 政和
Industrial Property Rights Holder
富山大学, ニプロ(株)
Industrial Property Number
特許特許第4341984号(分轄出願)
Acquisition Date
2009-07-17
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