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2010 Fiscal Year Final Research Report

Studies on the safety and efficacy of the simultaneous intake of the functional food.

Research Project

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Project/Area Number 19500710
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionNational Institute of Health and Nutrition

Principal Investigator

NAGATA Junichi  National Institute of Health and Nutrition, 食品保健機能プログラム, プロジェクトリーダー (70237527)

Project Period (FY) 2007 – 2010
Keywords食生活 / 健康 / 機能性食品 / 組み合せ
Research Abstract

In this study, we examined the beneficial function and the health effect of the functional food components or the so-called health foods in rats and mice. As a result, we could not observe the beneficial function in rats fed the excess amount of the so-called health food, although the excess intake did not influence any health effects such as growth and liver functions. On the other hand, the combinational intake of functional food components did not indicate the additive and/or synergetic effect or the cancel effect in rats and mice fed the experimental diets, although the individual component showed the certain beneficial function. In addition, we also did not observed any health effects in the appropriate use of the functional components. These results indicate that the combinational intake of the functional food components with similar health benefits does not show necessarily the better-than-expected performance. In addition, the functionality of the so-call health food is not clear even in the excess intake.

  • Research Products

    (15 results)

All 2010 2009 2008 2007 Other

All Journal Article (3 results) Presentation (8 results) Remarks (4 results)

  • [Journal Article] Effects of simultaneous intakes of soybean protein and diacylglycerol on lipid profiles and body fat accumulation in rats.2009

    • Author(s)
      Nagata J, Yamada K.
    • Journal Title

      Biosci. Biotechnol. Biochem. 73

      Pages: 1328-1332

  • [Journal Article] Foods with Health Claims in Japan.2008

    • Author(s)
      Nagata J, Yamada K.
    • Journal Title

      Food Sci.Technol.Res. 14

      Pages: 519-524

  • [Journal Article] Effects of dietary Angelica keiskei on serum and liver lipid profiles, and body fat accumulations in rats.2007

    • Author(s)
      Nagata J, Morino T, Saito M.
    • Journal Title

      J.Nutr.Sci.Vitaminol. 53

      Pages: 133-137

  • [Presentation] In vivo and in vitro studies on physiological functions of Ashitaba (Angelica Keiskei) and their extracts.2010

    • Author(s)
      永田純一, 中村礼, 石見佳子.
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Hawaii(USA)
    • Year and Date
      2010-12-19
  • [Presentation] 体脂肪低減をもたらす機能性食品素材の摂取が成長期マウス骨密度に及ぼす影響2010

    • Author(s)
      中村礼、石見佳子、永田純一
    • Organizer
      第57回日本栄養改善学会
    • Place of Presentation
      埼玉
    • Year and Date
      2010-09-12
  • [Presentation] β-コングリシニンと中鎖脂肪酸を含む食用油の併用摂取がマウスの体脂肪および脂質代謝に及ぼす影響2010

    • Author(s)
      中村礼、城内文吾、古場一哲、石見佳子、永田純一
    • Organizer
      第64回日本栄養・食糧学会
    • Place of Presentation
      徳島
    • Year and Date
      2010-05-23
  • [Presentation] Effects of Ashitaba (Angelica keiskei) extracts on lipid accumulations and gene expressions related to the lipid metabolism in cultured rat adipocytes.2009

    • Author(s)
      永田純一, 佐賀加奈子, 中村礼, 山田和彦
    • Organizer
      International Congress of Nutrition 2009
    • Place of Presentation
      Bangkok,(Thailand)
    • Year and Date
      2009-10-08
  • [Presentation] Effects of Simultaneous Intake of Soybean Protein and Diacylglycerol on Lipid Profiles and Body Fat Accumulation in Rats and Mice.2009

    • Author(s)
      Nagata J, Nakamura A, Shirouchi B, Ishimi Y.
    • Organizer
      38^<th> UJNR Food and Agriculture Panel Meeting.
    • Place of Presentation
      Tsukuba (Japan)
    • Year and Date
      2009-10-05
  • [Presentation] マウス体脂肪蓄積および脂質代謝関連遺伝子に及ぼす大豆タンパク質とジアシルグリセロール併用摂取の影響2009

    • Author(s)
      中村礼、佐賀加奈子、山田和彦、永田純一
    • Organizer
      第63回日本栄養・食糧学会
    • Place of Presentation
      長崎
    • Year and Date
      2009-05-22
  • [Presentation] ラット脂肪前駆細胞における明日葉抽出物の脂肪蓄積に対する影響2009

    • Author(s)
      永田純一、佐賀加奈子、中村礼、山田和彦
    • Organizer
      第63回日本栄養・食糧学会
    • Place of Presentation
      長崎
    • Year and Date
      2009-05-22
  • [Presentation] Effects of combination of some functional food components on lipid profiles in rats.2007

    • Author(s)
      永田純一
    • Organizer
      International Conference on Food Factor for Health Promotion.
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2007-11-30
  • [Remarks] 研究所定期刊行誌「健康・栄養ニュース」

  • [Remarks] 平成18年3月15日発行第4巻4号(通巻15号) Page 5.

  • [Remarks] 平成19年9月15日発行第6巻2号(通巻21号) Page 6.

  • [Remarks] 平成22年6月15日発行第9巻1号(第32号) Page 6.

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Published: 2012-01-26   Modified: 2016-04-21  

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