Study on Risk Diagnoses and Endovascular Therapy for Aneurysms

2008 Fiscal Year Final Research Report

• Project/Area Number: 19560160
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Fluid engineering
• Research Institution: Tokyo University of Agriculture and Technology
• Principal Investigator: TAKAKURA Yoko Tokyo University of Agriculture and Technology, 大学院・共生科学技術研究院, 助教 (10262239)
• Co-Investigator(Renkei-kenkyūsha): ARAI Norio 東京農工大学, 大学院・共生科学技術研究院, 教授 (20126288) ; KONISHI Yoshifumi 杏林大学, 保健学部, 教授 (10175333) ; FUKASAKU Kazuaki 理化学研究所, 生体力学シミュレーション特別研究ユニット, 客員主管研究員 (80283266)
• Project Period (FY): 2007 – 2008
• Keywords: バイオ流体力学

Research Abstract

動脈瘤の危険予知と血管内治療に関し,流体力学者の視点を中心に据えながら体外実験と数値計算を行いデータを蓄積した.主な研究成果は,(1) 分岐脳動脈瘤の発生・成長過程についての仮説を組み立て,(2) 分岐脳動脈瘤の破裂の危険性について論じた. さらに(3) ステント特性の評価法を提示し,(4) 効果的なステントの設計として流れ適合ステントを提示した.最後に(5) 血管内治療の安全性をめざしてステント装着,カテーテル挿入時の安全指針についても言及した.

Research Products

• [Journal Article] 脳動脈瘤の分岐部血流評価 (2008)
  • Author(s): 小西善史, 塩川芳昭, 深作和明, 竹内昌孝, 新井紀夫, 高倉葉子, 尾棹敦
  • Journal Title: In vitro study Pages: 311-316
  • Peer Reviewed
• [Journal Article] Characteristic Flow Phenomena on a Tee-Branch Pipe (2008)
  • Author(s): Atsushi OSAO, Yoko TAKAKURA, Norio ARAI
  • Journal Title: Journal of Visualization Vol.11, No.4 Pages: 283-284
  • Peer Reviewed
• [Journal Article] Numerical Simulation of Flows in a Pipe with an Aneurysmal Sac (Effects of Aneurysmal Models and Stents) (2008)
  • Author(s): Gulbahar, W., Kobori, T., Takakura,Y., Arai, N., Konishi, Y., and Fukasaku, K.
  • Journal Title: Advanced Materials Research Vols.33-37 Pages: 1025-1030
  • Peer Reviewed
• [Journal Article] Numerical Study on Flow-Adaptive Stents (2008)
  • Author(s): Takakura, Y., Gulbahar, W., Arai, N., Konishi, Y., and Fukasaku, K.
  • Journal Title: Stents," Advanced Materials Research Vols.33-37 Pages: 1031-1036
  • Peer Reviewed
• [Journal Article] In vitro Study on Branch Flows with a Cerebral Aneurysm (2008)
  • Author(s): Osao, A., Gulbahar W., Takakura,Y., Arai, N., Konishi, Y., and Fukasaku,K.
  • Journal Title: Advanced Materials Research Vols.33-37 Pages: 1037-1042
  • Peer Reviewed
• [Journal Article] 動脈瘤モデルを有する管内流れとステント特性 (2008)
  • Author(s): 高倉葉子, 小堀達也, 新井紀夫, 小西善史, 深作和明, 菊池伸匡
  • Journal Title: 日本機械学会論文集 74巻737号B編 Pages: 16-24
  • Peer Reviewed
• [Presentation] 動脈瘤への流れとカテーテルの影響の解析-安全な血管内治療を目指して (2009)
  • Author(s): 小西義史
  • Organizer: 第34回日本脳卒中学会
  • Place of Presentation: 松江
  • Year and Date: 2009-03-21
• [Presentation] 脳動脈瘤の分岐部血流評価 (2008)
  • Author(s): 小西善史, 塩川芳昭, 深作和明, 新井紀夫, 高倉葉子, 尾棹敦
  • Organizer: 第67回脳神経外科総会
  • Place of Presentation: 岩手
  • Year and Date: 20081001-03
• [Presentation] Endovascular Treatment of Intracranial Aneurysms : using new coils Clinical and experimental study (2008)
  • Author(s): Konishi Y
  • Organizer: the 8th Meeting of the Asian-Australasian Federation of Interventional, Therapeutic
  • Place of Presentation: Neuroradiology, Taiwan
  • Year and Date: 2008-04-18
• [Presentation] Numerical Study on Flow-Adaptive Stents (2007)
  • Author(s): Takakura, Y., Gulbahar W., Arai, N.,Konishi, Y., and Fukasaku, K.
  • Organizer: FEOFS2007
  • Place of Presentation: Urumqi, Xinjiang University, China
  • Year and Date: 2007-08-29
• [Presentation] In vitro Study on Branch Flows with a Cerebral Aneurysm (2007)
  • Author(s): Osao, A., Gulbahar W., Takakura, Y.,Arai, N., Konishi, Y., Fukasaku, K., and Kikuchi, N.
  • Organizer: FEOFS2007
  • Place of Presentation: Urumqi, Xinjiang University, China
  • Year and Date: 2007-08-29
• [Presentation] Numerical Simulation of Flows in a Pipe with an Aneurysmal Sac (Effects of Aneurysmal Models and Stents) (2007)
  • Author(s): Gulbahar W., Kobori, T., Takakura, Y., Arai, N., Konishi, Y., and Fukasaku, K.
  • Organizer: FEOFS2007
  • Place of Presentation: Urumqi, Xinjiang University, China
  • Year and Date: 2007-08-27