2009 Fiscal Year Final Research Report
Promotion of branching activity of epithelial tissues
| Project/Area Number |
19570054
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphology/Structure
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| Research Institution | Chiba University |
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Principal Investigator |
NOGAWA Hiroyuki Chiba University, 大学院・理学研究科, 准教授 (40143250)
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| Project Period (FY) |
2007 – 2009
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| Keywords | マウス胚 / 唾液腺 / 肺 / 分枝形態形成 / 成長因子 |
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| Research Abstract |
Branching is one of fundamental patterns of morphogenesis in developing organs of mammals. In the present study we revealed that the EGF family ligand-receptor system of embryonic mouse salivary glands becomes primed by the FGF ligand-receptor system to play an important role in the induction of branching morphogenesis. We also succeeded in introducing expression vectors into embryonic mouse lung epithelial tissues.
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