2009 Fiscal Year Final Research Report
Elucidation of degrading processes of polyunsaturated fatty acids by introducing a gene encoding polyhydroxyalkanoate synthase
| Project/Area Number |
19580080
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Utsunomiya University |
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Principal Investigator |
MAEDA Isamu Utsunomiya University, 農学部, 准教授 (10252701)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 不飽和脂肪酸 / ポリヒドロキシアルカン酸 / オレイン酸 / リノール酸 / リノレン酸 / 酵母 / Saccharomyces cerevisiae / β-酸化 |
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| Research Abstract |
When a polyunsaturated fatty acid contains the 12-cis double bond, dienoyl-CoA reductase activity has been shown to play an important role in β-oxidation of the fatty acid. As both linoleic acid and α-linolenic acid contain the 9-cis and 12-cis double bonds, it was suggested in α-linolenic acid that its inhibitory effect on β-oxidation and the higher necessity of dienoyl-CoA reductase activity in its metabolism might be due to the existence of 15-cis double bond.
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