2009 Fiscal Year Final Research Report
Salt-inducible chiral-nylon polymer from Bacillus megaterium : Synthesis and biochemical applications including an increase in halo-tolerance
| Project/Area Number |
19580092
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | Kochi University |
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Principal Investigator |
ASHIUCHI Makoto Kochi University, 教育研究部自然科学系, 准教授 (20271091)
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| Co-Investigator(Renkei-kenkyūsha) |
NAGATA Shinji 高知大学, 教育研究部自然科学系, 教授 (60180494)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 微生物遺伝・育種 / 環境材料 / 生体材料 / 生体機能利用 / バイオテクノロジー / 環境適応 |
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| Research Abstract |
We identified the industrial strain of Bacillus megaterium as a novel producer of L-type stereo-regular poly-γ-glutamate (PGA). Advanced analysis about PGA production of B. megaterium and cloning and sequencing of the genetic cluster responsible for the polymer synthesis and degradation, to examine stereo-regular PGA metabolism, were performed in the study. Additionally, in vivo and in vitro applicability of stereo-regular PGA as extremolyte-like materials was investigated as well.
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