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2008 Fiscal Year Final Research Report

Identification and functional analysis of the phenolamine receptor family

Research Project

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Project/Area Number 19580123
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Bioproduction chemistry/Bioorganic chemistry
Research InstitutionShimane University

Principal Investigator

OZOE Yoshihisa  Shimane University, 生物資源科学部, 教授 (80112118)

Project Period (FY) 2007 – 2008
Keywordsフェノールアミン / オクトパミン / チラミン / 生体アミン / Gタンパク質共役型レセプター / クローニング / カイコ / Bombyx mori
Research Abstract

フェノールアミンは、無脊椎動物の嗅覚、視覚、ストレス応答、記憶・学習など、様々な生理現象に関わる情報伝達物質である。フェノールアミンレセプターは、フェノールアミンを結合して、環境情報を細胞外から細胞内に伝える細胞膜タンパク質である。本研究では、レセプター遺伝子4種をカイコ(Bombyx mori)幼虫の神経組織から単離し、培養細胞に発現させて、個々のレセプターの機能と性質を明らかにした。

  • Research Products

    (8 results)

All 2009 2008 2007

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results)

  • [Journal Article] Bombyx mori phenolamine receptors: a comparative molecular biological study2008

    • Author(s)
      Y. Ozoe and J. Huang
    • Journal Title

      J. Pestic. Sci. 33

      Pages: 24-27

    • Peer Reviewed
  • [Journal Article] Single amino acid of an octopamine receptor as a molecular switch for distinct G protein couplings2008

    • Author(s)
      J. Huang, T. Hamasaki, F. Ozoe, and Y. Ozoe
    • Journal Title

      Biochemical and Biophysical Research Communications 371

      Pages: 610-614

    • Peer Reviewed
  • [Journal Article] Identification of critical structural determinants responsible for octopamine binding to the α-adrenergic-like Bombyx mori octopamine receptor2007

    • Author(s)
      J. Huang, T. Hamasaki, F. Ozoe, H. Ohta, K. Enomoto, H. Kataoka, Y. Sawa, A. Hirota, and Y. Ozoe
    • Journal Title

      Biochemistry 46

      Pages: 5896-5903

    • Peer Reviewed
  • [Presentation] カルシウム動員型カイコチラミン受容体のクローニングとその薬理学的特性2009

    • Author(s)
      太田広人、黄佳、井上典子、尾添富美代、尾添嘉久
    • Organizer
      日本農芸化学会2009年度大会、3P1048B、p.297
    • Year and Date
      2009
  • [Presentation] Mechanism of multiple functional coupling of a Bombyx mori octopamine receptor2008

    • Author(s)
      Y. Ozoe and J. Huang
    • Organizer
      XXIII International Congress of Entomology, No. 1405
    • Year and Date
      2008
  • [Presentation] Molecular pharmacological characterizations of insect biogenic amine receptors2007

    • Author(s)
      J. Huang and Y. Ozoe
    • Organizer
      Proceedings of 3rd International Symposium on Pesticide and Environmental Safety and 7th International Workshop on Crop Protection Chemistry and Regulatory Harmonization, III-005, pp.151-153,
    • Year and Date
      2007
  • [Presentation] Cloning and molecular characterization of a Bombyx mori β-adrenergic-like octopamine receptor2007

    • Author(s)
      X. Chen, H. Ohta, F. Ozoe, and Y. Ozoe
    • Organizer
      日本農薬学会第32回大会講演要旨集、B308、p.70
    • Year and Date
      2007
  • [Presentation] カイコから単離したオクトパミン受容体(BmOAR1)とチラミン受容体(BmTAR1)のリガンド応答2007

    • Author(s)
      濱崎智浩、黄佳、太田広人、尾添嘉久
    • Organizer
      日本農薬学会第32回大会講演要旨集、B307、p.69
    • Year and Date
      2007

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Published: 2010-06-10   Modified: 2016-04-21  

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