2009 Fiscal Year Final Research Report
Development of Reactions Catalyzed by Molybdenum Complexes with π-Ligands
| Project/Area Number |
19590021
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Nigata University of Phermacy and Applied Life Sciences |
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Principal Investigator |
SUGIHARA Takumichi Nigata University of Phermacy and Applied Life Sciences, 薬学部, 教授 (40222054)
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| Project Period (FY) |
2007 – 2009
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| Keywords | モリブデン / π-型配位子 / プロパルギル / ハロゲン化 |
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| Research Abstract |
We developed a couple of novel and efficient molybdenum-catalyzed reactions based on nature of π-type ligand which acted as both activation and stabilization of real catalytic species by the presence of equilibrium between σ- and π-type ligands. Our major findings were the follows ; 1) catalytic and nucleophilic substitution of allyl ethers by bromide ions delivered by molybdenum, 2) effect of π-propargyl ligands with various substituents on molybdenum to their catalytic activity, 3) cyclization of diynes catalyzed by molybdenum π-ligand complexes.
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