• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2008 Fiscal Year Final Research Report

ATP-evoked signals in glial nets associated with sensory devices : Their properties in propagation and coupling to functions

Research Project

  • PDF
Project/Area Number 19590184
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field General anatomy (including Histology/Embryology)
Research InstitutionHokkaido University

Principal Investigator

TAKAHASHI-IWANAGA Hiromi  Hokkaido University, 大学院・医学研究科, 准教授 (30193759)

Project Period (FY) 2007 – 2008
Keywords感覚神経終末 / 終末シュワン細胞 / カルシウム画像 / アデノシン5'三リン酸
Research Abstract

皮膚感覚装置グリア細胞は分岐する突起で連絡し合い、軸索終末間に広がる網をなす。このグリアの細胞外ATP刺激に対するCa応答について、伝播の時空特徴と制御因子を明らかにするため、ラット髭の動き受容器、槍型終末分離標本の生理実験と信号関連分子の組織化学を行なった。各軸索終末に伴行するグリア突起は、局所ATP刺激に対し独自のCa信号を生成し得る機能単位であり、信号の突起内局在化への細胞外ATP分解酵素の貢献が示された。

  • Research Products

    (11 results)

All 2009 2008 2007 Other

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (3 results) Remarks (1 results)

  • [Journal Article] Cellular expression of a monocarboxylate transporter (MCT1) in the mammary gland and sebaceous gland of mice2009

    • Author(s)
      Takebe K, Nio-Kobayashi J, Takahashi-Iwanaga H, Yajima T, Iwanaga T
    • Journal Title

      Histochem Cell Biol 131

      Pages: 401-409

    • Peer Reviewed
  • [Journal Article] Immunohistochemical localization of six galectin subtypes in the mouse digestive tract2009

    • Author(s)
      Nio-Kobayashi J, Takahashi-Iwanaga H, Iwanaga T
    • Journal Title

      J Histochem Cytochem 57

      Pages: 41-50

    • Peer Reviewed
  • [Journal Article] Histochemical demonstration of monocarboxylate transporter in the perineurium of mice with special reference to GLUT12008

    • Author(s)
      Takebe K, Nio-Kobayashi J, Takahashi-Iwanaga H, Iwanaga T
    • Journal Title

      Biomed Res 29

      Pages: 297-306

    • Peer Reviewed
  • [Journal Article] A dual system of intercellular calcium signaling in glial nets associated with lanceolate sensory endings in rat vibrissae2008

    • Author(s)
      Takahashi-Iwanaga H, Nio-Kobayashi J, Habara Y, Furuya K
    • Journal Title

      J Comp Neurol 510

      Pages: 68-78

    • Peer Reviewed
  • [Journal Article] Cellular expression of a sodium-dependent mono- carboxylate transporter (Slc5a8) and the MCT family in the mouse kidney2008

    • Author(s)
      Yanase H, Takebe K, Nio-Kobayashi J, Takahashi-Iwanaga H, Iwanaga T
    • Journal Title

      Histo- chem Cell Biol 130

      Pages: 957-966

    • Peer Reviewed
  • [Journal Article] Curriculum vitae of intestinal intraepithelial T cells: their develop- mental and behavioral characteristics2007

    • Author(s)
      Ishikawa H, Naito T, Iwanaga T, Takahashi-Iwanaga H, Suematsu M, Hibi T, Nanno M
    • Journal Title

      Immunol Rev 215

      Pages: 154-165

    • Peer Reviewed
  • [Journal Article] Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor2007

    • Author(s)
      Hisatsune C, Yasumatsu K, Takahashi-Iwanaga H, Ogawa N, Kuroda Y, Yoshida R, Ninomiya Y, Mikoshiba K
    • Journal Title

      J Biol Chem 282

      Pages: 37225-37231

    • Peer Reviewed
  • [Presentation] サル膵臓導管系介在部における水チャネルアクアポリン1の発現2009

    • Author(s)
      岩永ひろみ, 岩永敏彦
    • Organizer
      第114回日本解剖学会総会・全国学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2009-03-29
  • [Presentation] ラット頬ひげの槍型知覚終末におけるATPを介したグリア信号系2009

    • Author(s)
      岩永ひろみ
    • Organizer
      第113回日本解剖学会全国学術集会シンポジウム「皮膚・口腔領域における感覚研究の進展」
    • Place of Presentation
      由布
    • Year and Date
      2009-03-29
  • [Presentation] 皮膚・結合組織の知覚終末グリア細胞におけるecto-ATPaseの局在とその役割について2007

    • Author(s)
      岩永ひろみ
    • Organizer
      生理学研究所研究会「生体システム間境界領域におけるATP・アデノシン情報伝達の役割」
    • Place of Presentation
      岡崎
    • Year and Date
      2007-09-07
  • [Remarks]

    • URL

      http://www.med.hokudai.ac.jp/~anat-3w/kenkyu.htm

URL: 

Published: 2010-06-10   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi