2009 Fiscal Year Final Research Report
Multi-center case series study of lung injury associated with novel drugs for rheumatoid arthritis treatment
Project/Area Number |
19590530
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied pharmacology
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Research Institution | Tokyo Medical and Dental University |
Principal Investigator |
KOIKE Ryuji Tokyo Medical and Dental University, 医学部附属病院, 准教授 (50250220)
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Co-Investigator(Kenkyū-buntansha) |
HARIGAI Masayoshi 東京医科歯科大学, 医歯学総合研究科, 客員教授 (20238207)
MIYASAKA Nobuyuki 東京医科歯科大学, 医歯学総合研究科, 教授 (30157622)
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Project Period (FY) |
2007 – 2009
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Keywords | 医薬品副作用 / 抗リウマチ薬 / 関節リウマチ / ニューモシスチス肺炎 / 薬剤性肺炎 |
Research Abstract |
We have studied pulmonary complications associated with novel drugs approved for rheumatoid arthritis treatment recently. We have focused on the Pneumocystis pneumonia under infliximab or etanercept treatment and drug-induced pneumonia under tacrolimus treatment. And we have constructed and arranged the database of Japanese rheumatoid arthritis patients, which is essential for the research of adverse reactions induced by anti-rheumatic drugs.
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[Journal Article] Japan College of Rheumatology 2009 guidelines for the use of tocilizumab, a humanized anti-interleukin-6 receptor monoclonal antibody, in rheumatoid arthritis2009
Author(s)
Koike R, Harigai M, Atsumi T, Amano K, Kawai S, Saito K, Saito T, Yamamura M, Matsubara T, Miyasaka N.
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Journal Title
Mod Rheumatol 19
Pages: 351-7
Peer Reviewed
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