2010 Fiscal Year Final Research Report
Hair has known the history of drugs abused
| Project/Area Number |
19590672
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Hiroshima University |
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Principal Investigator |
NISHIDA Manami Hiroshima University, 技術センター, 技術専門員 (60379914)
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| Co-Investigator(Kenkyū-buntansha) |
NAMERA Akira 広島大学, 大学院・医歯薬学総合研究科, 准教授 (30284186)
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| Project Period (FY) |
2007 – 2010
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| Keywords | 分析化学 / 乱用薬物 / 覚せい剤 / 毛髪 / 固相マイクロ抽出 |
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| Research Abstract |
The drug abuse is a serious problem in the world. Analysis of the drugs in human hair is very important to reveal the history of the drug abuse. So far, there has no report of a high sensitive determination method for determination of methamphetamine and amphetamine from a limited material such as a small piece of human hair. We developed a high sensitive and accurate method by using headspace solid phase microextraction. As a result, it was possible to determine the drugs from one piece of hair(1cm). The detection limit of this method was 20 and 50 pg for methamphetamine and amphetamine, respectively. The proposed method will be helpful to judge the period of the drug abuse without a pain for a patient.
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