2008 Fiscal Year Final Research Report
Interventional approaches to chronic lung diseases by regulation of matrix metalloproteinases
| Project/Area Number |
19590877
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Hokkaido University |
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Principal Investigator |
BETSUYAKU Tomoko Hokkaido University, 大学院・医学研究科, 准教授 (60333605)
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| Project Period (FY) |
2007 – 2008
|
| Keywords | EMMPRIN / basigin / MMP / 上皮細胞 / 再生 |
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| Research Abstract |
本研究はMatrix metalloproteinases (MMPs) の発現を誘導する膜型糖蛋白basigin/EMMPRIN (extracellular matrix metalloproteinase inducer) という分子に注目し、肺における生理的役割、様々な病態における役割について明らかにした。
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