2010 Fiscal Year Final Research Report
Research and development of therapeutic antibodies against human rotavirus infection.
| Project/Area Number |
19591266
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatrics
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| Research Institution | Fujita Health University |
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Principal Investigator |
MORIGUCHI Kyoko Fujita Health University, 医学部, 講師 (60298528)
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| Co-Investigator(Kenkyū-buntansha) |
TANIGUCH Ikoki 藤田保健衛生大学, 医学部, 教授 (40094213)
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| Project Period (FY) |
2007 – 2010
|
| Keywords | ヒト型ファージ抗体 / 交叉反応性 / ロタウイルス / ノロウイルス |
|---|
| Research Abstract |
Expression system of human antibodies in Lactococcus lactise was established to be enable to produce the molecules persistently in intestine. We also tried to isolate anti-human norovirus antibodies, and 66 clones (42types) including2cross-reactive antibodies were isolated.
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