2009 Fiscal Year Final Research Report
Gene silencing of STAT6 with siRNA ameliorates contact hypersensitivity and allergic rhinitis
| Project/Area Number |
19591297
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dermatology
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
YOKOZEKI Hiroo Tokyo Medical and Dental University, 医歯学総合研究科, 教授 (90210608)
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| Co-Investigator(Kenkyū-buntansha) |
SATOH Takahiro 東京医科歯科大学, 医歯学総合研究科, 准教授 (30235361)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 皮膚炎症 / 再生学 |
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| Research Abstract |
We established the gene therapy targeting for STAT6. We demonstrated that gene siliencing of STAT6 with siRNA ameliorates both contact hypersensitivity and allergic rhinitis by using model mouse.
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