2010 Fiscal Year Final Research Report
A study about the improvement of QOL after gastric cancer surgery and the medical cost restraint.
| Project/Area Number |
19591553
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Digestive surgery
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| Research Institution | Yokohama City University |
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Principal Investigator |
RINO Yasushi Yokohama City University, 医学部, 准教授 (50254206)
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| Co-Investigator(Kenkyū-buntansha) |
IMADA TOSHIO 横浜市立大学, 附属病院, 教授 (50168514)
YUKAWA NORIO 横浜市立大学, 附属病院, 准教授 (40336558)
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| Project Period (FY) |
2007 – 2010
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| Keywords | 胃癌術後 / ビタミン / 医術後障害 / 医療費抑制 |
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| Research Abstract |
Clinical assesment
1. Serum Vitamin A and E levels after gastrectomy for gastric cancer
Serum vitamin A levels decreased in 1.8% and serum E levels in 21.8%. We assume that vitamin E deficiency is more common than thought. Low vitamin E was associated significantly with low total cholesterol.
2. Serum Vitamin E levels after gastrectomy for gastric cancer in early phase
Serum vitamin E level was decreased in 21.7% patients. We assume that vitamin E deficiency more likely occurs after the reconstruction procedure in which food does not pass through the duodenum in early phase after gastrectomy. Transport disturbance with loss of passage through the duodenum consequently may be the major cause of malabsorption.
Animalexperiment
In total gastrectomy rats, the incidence of low vitamin E was significantly higher in non-gastrectomy rats.
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[Journal Article] 胃癌術後のビタミンA,Eの変化とその臨床学的意義について2007
Author(s)
利野靖, 上田直久, 湯川寛夫, 佐伯博行, 金成正浩, 藤井慶太, 鈴木ゆめ, 黒岩義之, 益田宗孝, 今田敏夫
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Journal Title
日本消化器外科学会雑誌 (0386-9768)40巻11号
Pages: 1763-1768
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[Presentation] 胃癌術後のビタミンDについて2008
Author(s)
利野靖, 山本裕司、和田修幸,湯川寛夫, 村上仁志, 鈴木誠, 松浦仁、荒井宏雅、山中澄隆、益田宗孝, 今田敏夫
Organizer
第109回日本外科学会総会
Place of Presentation
長崎
Year and Date
20080515-20080517
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