2009 Fiscal Year Final Research Report
Development of functional imaging in joint abnormalities for sensitive assessment of drug efficacy
| Project/Area Number |
19591757
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Osaka University |
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Principal Investigator |
NISHII Takashi Osaka University, 医学系研究科, 寄附講座准教授 (70304061)
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| Co-Investigator(Kenkyū-buntansha) |
KURODA Kagayaki 東海大学, 情報理工学部, 准教授 (70205243)
SUGANO Nobuhiko 大阪大学, 医学系研究科, 教授 (70273620)
TANAKA Hisashi 大阪大学, 医学系研究科, 講師 (40294087)
SATO Yoshinobu 大阪大学, 医学系研究科, 准教授 (70243219)
SAKAI Takashi 大阪大学, 医学部附属病院, 助教 (00444539)
MATSUOKA Yuichirou 先端医療振興財団, 分子イメージング研究グループ, 研究員 (80372150)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 関節病学 |
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| Research Abstract |
To allow sensitive evaluation of early cartilage abnormalities in the hip or knee joints, we developed quantitative MR imaging system under in-situ loading system. By experimental and clinical studies, cartilage T2 mapping by loading was indicated as a promising index for evaluating early cartilage abnormalities and abnormal biomechanical conditions around the articular cartilage.
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