Molecular genetic analysis of recurrence in endogenous uveitis

2009 Fiscal Year Self-evaluation Report

• Project/Area Number: 19592003
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Hokkaido University
• Principal Investigator: KITAICHI Nobuyoshi Hokkaido University, 北海道大学病院, 助教 (40431366)
• Project Period (FY): 2007 – 2010
• Keywords: 遺伝子 / 分子遺伝学 / 臨床 / ベーチェット病 / Vogt-小柳-原田病

Research Abstract

本研究ではぶどう膜炎における人類普遍の疾患感受性遺伝子や予後に影響を与える遺伝子を検索する。なかでも再発に特に注目しており、ぶどう膜炎を再発しやすい疾患としにくい疾患、再発しやすい患者としにくい患者を分子遺伝学的に検討する。

Research Products

• [Journal Article] prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian people. (2009)
  • Author(s): Kitaichi N, Miyazaki A, Stanford MR, Iwata D, Chams H, Ohno S. Low
  • Journal Title: Br J Ophthalmol 93 Pages: 1428-1430
• [Journal Article] Association of TLR4 polymorphism with Behcet disease in Korean population. (2009)
  • Author(s): Horie Y, Meguro A, Ota M, Kitaichi N, Katsuyama Y, Takemoto Y, Namba K, Yoshida K, Song YW, Park KS, Lee, EB, Inoko H, Mizuki N, Ohno S.
  • Journal Title: Rheumatology 48 Pages: 638-642
• [Journal Article] Evaluation of PTPN22 polymorphisms and Vogt-Koyanagi-Harada disease in Japanese patients. (2009)
  • Author(s): Horie Y, Kitaichi N, Yoshida K, Katsuyama Y, Yoshida K, Miura T, Ota M, Asukata Y, Inoko H, Mizuki N, Ishida S, Ohno S.
  • Journal Title: Mol Vis 15 Pages: 1115-1119
• [Journal Article] Ocular features of Behcet's disease : An international collaborative study. (2007)
  • Author(s): Kitaichi N, Miyazaki A, Stanford MR, Chams H, Iwata D, Ohno S.
  • Journal Title: Br J Ophthalmol. 91 Pages: 1579-82
• [Presentation] Low prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian people (2009)
  • Organizer: 2^<nd> International Uveitis & 3^<rd> Asia-Pacific Intraocular Inflammation Sympoium
  • Place of Presentation: Chongqing, China
  • Year and Date: 2009-11-06
• [Book] 治療薬ハンドブック2010(高久史麿監修, 堀正二, 菅野健太郎, 門脇孝, 乾研一, 林昌洋 (編集著)) (2010)
  • Author(s): 北市伸義 (分担執筆)
  • Total Pages: 1435
  • Publisher: じほう
• [Patent(Industrial Property Rights)] ぶどう膜炎の予防及び/または治療のための医薬 (2008)
  • Inventor(s): 北市伸義
  • Industrial Property Rights Holder: 北海道大学・興和
  • Industrial Property Number: 特許権特願2008-323057号
  • Filing Date: 2008-12-19