Study of dynamic contrast-enhanced MRI in the maxillofacial region

2009 Fiscal Year Final Research Report

• Project/Area Number: 19592170
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Okayama University
• Principal Investigator: ASAUMI Junichi Okayama University, 大学院・医歯薬学総合研究科, 教授 (60184131)
• Co-Investigator(Kenkyū-buntansha): KONOUCHI Hironobu 岡山大学, 岡山大学病院, 講師 (20294423) ; YANAGI Yoshinobu 岡山大学, 岡山大学病院, 助教 (50284071) ; HISATOMI Miki 岡山大学, 大学院・医歯薬学総合研究科, 助教 (60314704) ; MATSUZAKI Hidenobu 岡山大学, 医学部・歯学部附属病院, 助教 (70325124)
• Project Period (FY): 2007 – 2009
• Keywords: ダイナミックMRI / 口腔扁平上皮癌 / contrast index / PCNA / microvessel density / 腫瘍血管新生 / 腫瘍増殖能

Research Abstract

The histopathological prognostic factors, tumor proliferation and microvessel density (MVD) showed significant correlations with enhancement parameters in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in oral squamous cell carcinoma (SCC). The assessment of DCE-MRI parameters may prove to be a valuable non-invasive method for assessing tumor cell proliferation and MVD of patients with oral cancer.

Research Products

• [Journal Article] A case of malignant fibrous histiocytoma of the maxillary sinus (2010)
  • Author(s): Yanagi Y, Murakami J, Hisatomi M, Katase N, Nagatsuka H, Asaumi J
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109(3) Pages: e99-e104
  • Peer Reviewed
• [Presentation] 単純性骨嚢胞の診断における造影MRI・ダイナミックMRIの有用性に関する研究 (2009)
  • Author(s): 柳文修, 浅海淳一, 畦坪輝寿, 松崎秀信, 此内浩信, 村上純, 久富美紀
  • Organizer: 日本歯科放射線学会第14回臨床画像大会
  • Place of Presentation: 札幌
  • Year and Date: 20091024-20091025
• [Presentation] Usefulness of MRI in thdiagnosis of lesions in the jawbone (2009)
  • Author(s): Konouchi H, Yanagi Y, Hisatomi M, Matsuzaki H, Unetubo T, Katashima K, Ashida M, Asaumi J
  • Organizer: 17th International Congress of Dentomaxillofacial Radiology
  • Place of Presentation: Amsterdam, The Netherlands
  • Year and Date: 20090628-20090702
• [Presentation] Dynamic contrast-enhanced magnetic resonance imaging for estimating tumor proliferation and microvessel density of oral squamous cell carcinomas (2009)
  • Author(s): Unetsubo T, Konouchi H, Yanagi Y, Murakami J, Matsuzaki H, Hisatomi M, Asaumi J
  • Organizer: 17th International Congress of Dentomaxillofacial Radiology
  • Place of Presentation: Amsterdam, The Netherlands
  • Year and Date: 20090628-20090702
• [Presentation] 唾液腺腫瘍におけるdynamic contrast-enhanced MRIの有用性の検討 (2009)
  • Author(s): 久富美紀, 柳文修, 此内浩信, 浅海淳一
  • Organizer: 第63回NPO法人日本口腔科学会学術集会
  • Place of Presentation: 浜松
  • Year and Date: 20090416-20090417
• [Presentation] Dynamic MRIによる血流評価が有用であった下顎骨脈瘤性骨嚢胞の一例 (2009)
  • Author(s): 藤田麻理子, 柳文修, 久富美紀, 此内浩信, 浅海淳一
  • Organizer: 第57回npo法人日本口腔科学会中国・四国地方部会
  • Place of Presentation: 倉敷
  • Year and Date: 2009-11-14
• [Presentation] Dynamic contrast-enhanced magnetic resonance imaging for establishing tumor proliferation and microvessel density of oral squamous cell carcinoma (2008)
  • Author(s): Unetsubo T, Konouchi H, Yanagi Y, MurakamiJ, Matsuzaki H, Hisatomi M, Asaumi J
  • Organizer: The 7th Asian Congress of Oral and Maxillo-Facial Radiology (ACOMFR2008) and The 13th Annual Meeting of Clinical Diagnostics of the Japanese Society for Oral and Maxillofacial Radiology (JSOMR)
  • Place of Presentation: Nara, Japan
  • Year and Date: 20081120-20081122
• [Presentation] MRIを用いた顎骨内病変の鑑別 (2008)
  • Author(s): 此内浩信, 柳文修, 久富美紀, 松崎秀信, 芦田昌和, 片嶋和典, 浅海淳一
  • Organizer: 第21回日本口腔診断学会学術集会
  • Place of Presentation: 東京
  • Year and Date: 20080919-20080920
• [Remarks] Asaumi J、Differential diagnosis of oral lesions、XVI JABRO, Jornada da Associacao Brasileira de Radiologia Odontologica、2009.09.05、Ouro Preto、Brazil(2)Asaumi J、DIAGNOSTICO
• [Remarks] Asaumi J、DIAGNOSTICO DIFERENCIAL DA REGIAO DE CABECA E PESCOCO、2009.08.21、Sao Paulo、Brasil
• [Remarks] Kurabayashi T and Asaumi J、CT/MRI of the Head and Neck、The 7th Asian Congress of Oral and Maxillo-Facial Radiology (ACOMFR2008) and The 13th Annual Meeting of Clinical Diagnostics of the Japanese Society for Oral and Maxillofacial Radiology (JSOMR)、2008.11.20-22, Nara、2008.11.22 Nara、Japan